Protein Alignment clt and Ache

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_038945765.1
• Gene: Ache / 83817
• RGDID: 69313
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 175/531 - (32%)
• Similarity: 259/531 - (48%)
• Gaps: 82/531 - (15%)

  Fly    22 VPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQR 86
            |.|:.|.|.|.:.|...| ..::|||:|:||||||..||..|.| :|.....||.:...||.||.
  Rat    41 VRVRGGQLRGIRLKAPGG-PVSAFLGIPFAEPPVGSRRFMPPEP-KRPWSGILDATTFQNVCYQY 103

  Fly    87 -DPFTLEVAG----------SEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPA 140
             |.......|          |||||:|||:.|..:.| :|.||::||:||||:.|..:.|.:...
  Rat   104 VDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLIWIYGGGFYSGASSLDVYDGR 167

  Fly   141 KLMEQE-VIVVTLNYRLGALGFLSLP-EEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFG 203
            .|.:.| .::|::|||:|..|||:|| .....||:||.||||||:|||||||:|.|||.:|||||
  Rat   168 FLAQVEGTVLVSMNYRVGTFGFLALPGSRDAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFG 232

  Fly   204 ESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEW--VFQNEAPAKTRRLAELLG--GGDFGGDS 264
            ||||.:||.:|..:..::.|||:|::||||.|..|  |...||..:...||.|:|  .|..||:.
  Rat   233 ESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGND 297

  Fly   265 KALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVED---SSSPDRFLEQ-DIMELMH 325
            ..|::.|::..|..  ::.:...||..:...|   |:|.|||:.   |.:|:..:.. |..:|.
  Rat   298 TELISCLRTRPAQD--LVDHEWHVLPQESIFR---FSFVPVVDGDFLSDTPEALINTGDFQDLQ- 356

  Fly   326 KKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDP---QAPEAQEAASDIR 387
                     |::|....||...:|..   :..:..|...|:.|...|..   ..|:|.:.|::..
  Rat   357 ---------VLVGVVKDEGSYFLVYG---VPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAV 409

  Fly   388 AFFFNGQALSKENMDNLVDLFS----DYHFSMDL-QRAVEIHASCQTQSPLYFYRLDYVGGRNLY 447
            ...:. ..|..|:..:|.|..|    |::....: |.|..:.|.                |..:|
  Rat   410 VLHYT-DWLHPEDPAHLRDAMSAVVGDHNVVCPVAQLAGRLAAQ----------------GARVY 457

  Fly   448 KKIFQNED-------LRGVAHADDICYLFQMAGDET-EMNRDDLMVTERLCEMWANFARDGKP-- 502
            ..||::..       ..||.|..:|.::|.:..|.: ....::.:..:||.:.|.||||.|.|
  Rat   458 AYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTVEERIFAQRLMKYWTNFARTGDPND 522

  Fly   503 -----SPIWKP 508
                 ||.|.|
  Rat   523 PRDSKSPRWPP 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	175/531 (33%)
Ache	XP_038945765.1	COesterase	37..563	CDD:395084	175/531 (33%)