Protein Alignment clt and Ces5a

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001368779.1
• Gene: Ces5a / 67935
• MGIID: 1915185
• Length: 579
• Species: Mus musculus
• Alignment Length: 550
• Identity: 168/550 - (30%)
• Similarity: 266/550 - (48%)
• Gaps: 77/550 - (14%)

  Fly    25 KQGVLVGRQKKLVNGLE-YNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQRDP 88
            |.|.:.|:|..::..|| .|.|||:|:|.||:|.|||..|:|...:.... :.:...|:.:|
Mouse    40 KLGWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSKPQPPIPWDNLR-EATAYPNLCFQ--- 100

  Fly    89 FTLE--------------VAG-SEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHF 138
             .||              :.| |||||:||:|||...:..:.|||||||.||||..|:. |.|..
Mouse   101 -NLEWLFIYQNLLKVSYPILGMSEDCLYLNIYAPCHANNGSSLPVMVWIPGGGFETGSA-SIFDG 163

  Fly   139 PAKLMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFG 203
            .|..:.::|:|||:.||||..||.:...:...||....||..||.||:|||..|.|:|::||:||
Mouse   164 SALAVYEDVLVVTIQYRLGIFGFFTTQNQHAPGNWAFWDQLAALLWVRENIKYFGGNPDSVTIFG 228

  Fly   204 ESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFG-GDSKAL 267
            .|||..|:.....:..:..|||:||||||.|.:..:..::...| ..|..:....|.. .|||||
Mouse   229 NSAGAISISSLILSPLSADLFHRAIMQSGVAIIPSLKSSDNDLK-HDLQVVANVCDCNVSDSKAL 292

  Fly   268 LTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGS 332
            |..|:.:         ::|:::|..::.:    :|..||:.|     |..::.:||:.:| .|..
Mouse   293 LKCLREK---------SSLELMSLSQKAK----SFTRVVDGS-----FFSEEPLELLSQK-TLKI 338

  Fly   333 MPVIMGYNSAE-GLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFNGQAL 396
            :|.|:|.|:.| |..:.|:...::....::...|...:.:|............:    :|:|:..
Mouse   339 VPSIIGVNNQECGYILPVRDTPEILLGSNESTALTLIHTLLHIPTQHLYIVTKE----YFHGKHS 399

  Fly   397 SKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVA- 460
            ..:..|.|:|||.|..|.:........|.  .:..|:|||...:      ....|||.....|.
Mouse   400 PTDIRDTLLDLFGDVFFVVPGLVTARYHR--DSGGPVYFYEFQH------RPHCFQNSRPAFVKA 456

  Fly   461 -HADDICYLFQ---MAGDET---EMNRDDLMVTERLCEMWANFARDGKPS----PIWKPVKKPHN 514
             |.|:|.::|.   :.||..   |...::.:::.::.:.||||||.|.|:    |.| || ...|
Mouse   457 DHTDEIRFVFGGPFLKGDVVMFEEATEEEKLLSRKMMKYWANFARSGDPNGADLPPW-PV-YDEN 519

  Fly   515 GEPIQLDC-LLIDRELKMCSNPDGERMDFW 543
            .:.::||. :...|.||      .:|::||
Mouse   520 EQYLELDVNISTGRRLK------DQRVEFW 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	166/548 (30%)
Ces5a	NP_001368779.1	COesterase	33..543	CDD:395084	166/548 (30%)