Protein Alignment clt and Aadac

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_075872.1
• Gene: Aadac / 67758
• MGIID: 1915008
• Length: 398
• Species: Mus musculus
• Alignment Length: 333
• Identity: 69/333 - (20%)
• Similarity: 125/333 - (37%)
• Gaps: 89/333 - (26%)

  Fly    72 QELDCSKEGNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKS--TRTPLPVMVWIHGGGFFFGNGNS 134
            ||:..:.:.:|:.....|        |.:.:.:|.||.||  .|..|   .:|||||:..|   |
Mouse    68 QEVPPTSDEHVTVMETAF--------DSVPVRIYIPKRKSMALRRGL---FYIHGGGWCLG---S 118

  Fly   135 DFHFPAKLMEQ------EVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEW-VQENIASF 192
            ..||....:.:      :.:||:.:|.|.       |:.  |.....:|...:|.| :||::...
Mouse   119 AAHFSYDTLSRWTAHKLDAVVVSTDYGLA-------PKH--HFPRQFEDVYRSLRWFLQEDVLEK 174

  Fly   193 NG-DPNNVTLFGESAGGSSVHLHT----------FARHAKRLFHKAIMQSGTANMEWVFQNEAPA 246
            .| ||..|.:.|:||||:.....|          .....:.|.:.|:....|         ..|:
Mouse   175 YGVDPRRVGVSGDSAGGNLAAAVTQQLIQDPDVKIKLKVQALIYPALQALDT---------NVPS 230

  Fly   247 KTRRLAELLGGGDFGGDSKALLT-----FLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVV 306
            :..       |..|...:::|:.     :..:::....|:|.|           :|:|.....::
Mouse   231 QQE-------GSHFPVLTRSLMVRFWSEYFTTDRGLEKAMLLN-----------QHVPMESSHLL 277

  Fly   307 E----DSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVP 367
            :    .|..|:|:.:..:    :|....||..:...|..    .|.|||...|.  .|::...:|
Mouse   278 QFVNWSSLLPERYKKSPV----YKNPTPGSSELAQKYPG----FIDVKACPLLA--NDNILHHLP 332

  Fly   368 RNLVLDPQ 375
            :..::..|
Mouse   333 KTYIITCQ 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	69/333 (21%)
Aadac	NP_075872.1	Abhydrolase_3	106..356	CDD:400284	58/287 (20%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	110..112		1/1 (100%)