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Protein Alignment clt and BCHE

DIOPT Version :9

Sequence 1:	NP_536784.1	Gene:	clt / 117300	FlyBaseID:	FBgn0000326	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_000046.1	Gene:	BCHE / 590	HGNCID:	983	Length:	602	Species:	Homo sapiens

Alignment Length:	633	Identity:	180/633 - (28%)
Similarity:	286/633 - (45%)	Gaps:	147/633 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 CGRLIFTRFCSSMKV-KVPVKQGVLVGRQKKLVNGLE-------YNSFLGVPYAEPPVGELRFRS 62
            |.|.:|......|.: |...:..:::..:...|.|:.       ..:|||:|||:||:|.|||:.
Human     9 CIRFLFWFLLLCMLIGKSHTEDDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRLRFKK 73

  Fly    63 PRPLERFQK------------QELDCSKEG-NVSYQRDPFTLEVAGSEDCLFLNVY--APKVKST 112
            |:.|.::..            |.:|.|..| :.|...:|.|   ..|||||:|||:  |||.|:.
Human    74 PQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNT---DLSEDCLYLNVWIPAPKPKNA 135

  Fly   113 RTPLPVMVWIHGGGFFFGNGNSDFH-FPAKLME--QEVIVVTLNYRLGALGFLSLP-EEGIHGNM 173
                .|::||:|||  |..|.|..| :..|.:.  :.||||::|||:||||||:|| .....|||
Human   136 ----TVLIWIYGGG--FQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNM 194

  Fly   174 GLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEW 238
            ||.||:|||:|||:|||:|.|:|.:|||||||||.:||.||..:..:..||.:||:|||:.|..|
Human   195 GLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPW 259

  Fly   239 VFQN--EAPAKTRRLAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVL---SPDERRRHL 298
            ...:  ||..:|..||:|.|..  ..:...::..|:::  .|..||.|...|:   :|      |
Human   260 AVTSLYEARNRTLNLAKLTGCS--RENETEIIKCLRNK--DPQEILLNEAFVVPYGTP------L 314

  Fly   299 PFAFKPVVED---SSSPDRFLEQDIMELMHKKDCLGSM---PVIMGYNSAEGLAIVVKAKQKLEA 357
            ...|.|.|:.   :..||..||            ||..   .:::|.|..||.|.:|..   ...
Human   315 SVNFGPTVDGDFLTDMPDILLE------------LGQFKKTQILVGVNKDEGTAFLVYG---APG 364

  Fly   358 YEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFNGQALSKENM-----------------DNLV 405
            :..|...::.|.        |.||.   ::.||.......||::                 :.|.
Human   365 FSKDNNSIITRK--------EFQEG---LKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALG 418

  Fly   406 DLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLR-------GVAHAD 463
            |:..||:|            .|..   |.|.:.....|.|.:...|::...:       ||.|..
Human   419 DVVGDYNF------------ICPA---LEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGY 468

  Fly   464 DICYLFQMAGDETE-MNRDDLMVTERLCEMWANFARDGKPS---------PIWKPVKKPH---NG 515
            :|.::|.:..:..: ..:.:.:::..:.:.|||||:.|.|:         |::|..::.:   |.
Human   469 EIEFVFGLPLERRDNYTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNT 533

  Fly   516 EPIQLDCLL-----------IDRELKMCSNPDGERMDFWRSMYRRYRS 552
            |..::...|           ..:.|:|..|.|....: |::.:.|:.:
Human   534 ESTRIMTKLRAQQCRFWTSFFPKVLEMTGNIDEAEWE-WKAGFHRWNN 580

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.