Protein Alignment clt and nlgn3a

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 605
• Identity: 172/605 - (28%)
• Similarity: 258/605 - (42%)
• Gaps: 159/605 - (26%)

  Fly     1 MLLRPCG--RLIFTRFCSSMKVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSP 63
            ||:|..|  ..:.|::......:||:...:|.          ..:.:||||||.|||||.||..|
Zfish    60 MLVRGQGYYPTVNTQYGKLRGARVPLHSEILG----------PVDQYLGVPYATPPVGEKRFLPP 114

  Fly    64 RPLERFQ--KQELD----CSKEGNVSYQRDP---------FTLEVAG------SEDCLFLNVYAP 107
            .|...:.  |....    |.:  |: :...|         |.|::..      :||||:||:|.|
Zfish   115 EPPSSWSGIKNATHFAPVCPQ--NI-HNAVPEIMMPIWFTFNLDIVATSIQDQNEDCLYLNIYVP 176

  Fly   108 -------KVKSTRTP-----------------------------------LPVMVWIHGGGFFFG 130
                   ..:.||.|                                   .||||:||||.:..|
Zfish   177 TEDVKRISKECTRKPNKKICRKGGTHSKKQGEDLSDNDGDEDEDIRDTGAKPVMVYIHGGSYMEG 241

  Fly   131 NGNSDFHFPAKLMEQ--EVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFN 193
            .||.   ....::..  .|||:|||:|:|.|||||..::...||.||.||..||.|:.|||..|.
Zfish   242 TGNM---IDGSVLASYGNVIVITLNFRVGVLGFLSTGDQAAKGNYGLLDQIQALRWISENIGYFG 303

  Fly   194 GDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAK-TRRLAELLGG 257
            ||.|.:|:||...|.|.|.|.|.:.|::.|||:||:|||:|...|.. |..|.| ||.|||.:|.
Zfish   304 GDSNRITVFGSGIGASCVSLLTLSHHSEGLFHRAIIQSGSALSSWAV-NYQPVKYTRLLAEKVGC 367

  Fly   258 GDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPD--------- 313
            ...  |:..::..|:.:.|.         :::..|.:......||.||::....||
Zfish   368 NVL--DTLDMVDCLRKKSAR---------ELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQG 421

  Fly   314 RFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAI---VVKAKQKLEAYEDDLARLVPRNLVLD-- 373
            .||..|||               :|.|..|||..   ||.::..:...:.|.:       |.|
Zfish   422 EFLNYDIM---------------LGVNQGEGLRFVENVVDSEDGVSGNDFDFS-------VSDFV 464

  Fly   374 ---PQAPEAQEAASDIRAFFFNGQALSKENMD----NLVDLFSDYHFSMDLQRAVEIHASCQTQS 431
               ...||.::...:...|.:...| .::|.:    .||.||:|:.:........::||  :..|
Zfish   465 DSLYGYPEGKDTLRETIKFMYTDWA-DRDNPETRRKTLVALFTDHQWVEPSVVTADLHA--RYGS 526

  Fly   432 PLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLF--QMAGDETEM-----NRDDLMVTERL 489
            |.|||.. |...::|.|..:.:     .||.|::.|:|  .|.| .|::     :::|:|::..:
Zfish   527 PTYFYAF-YHHCQSLMKPAWSD-----AAHGDEVPYVFGIPMIG-PTDLFPCNFSKNDIMLSAVV 584

  Fly   490 CEMWANFARDGKPSPIWKPV 509
            ...|.|||:.|.|:   |||
Zfish   585 MTYWTNFAKTGDPN---KPV 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	167/582 (29%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	168/596 (28%)