Protein Alignment clt and ces2b

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_021326380.1
• Gene: ces2b / 561967
• ZFINID: ZDB-GENE-041014-96
• Length: 1611
• Species: Danio rerio
• Alignment Length: 613
• Identity: 181/613 - (29%)
• Similarity: 266/613 - (43%)
• Gaps: 124/613 - (20%)

  Fly     9 LIFTRFCSSMKVK-VPVKQ---GVLVGRQKKLVNGLE--YNSFLGVPYAEPPVGELRFRSPRPLE 67
            ||.....:|:|.: .|:.|   |.|.|.|.| ..|.:  .:|:||:|:|:||||.||...|:|.|
Zfish    14 LIAVTLQNSVKAEDGPILQTNSGALKGLQMK-ARGKDTVIHSYLGIPFAKPPVGPLRLAPPQPAE 77

  Fly    68 RFQ------KQELDCSKE--------GNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPV 118
            :::      ||.|.|.::        .|:|.:.|    .|..|||||:||||.|........|||
Zfish    78 KWEGVRDATKQPLMCLQDRQLVEDLVANLSAKVD----MVDSSEDCLYLNVYTPSKPGRNDKLPV 138

  Fly   119 MVWIHGGGFFFGNGN-SDFHFPAKLMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLAL 182
            |||||||||...:.: .|.|..|..  |:|:||.:.||||.|||.|..:|...||.||.||..||
Zfish   139 MVWIHGGGFTTCSASLFDGHVLAAY--QDVVVVVIQYRLGLLGFFSTGDENAPGNYGLLDQVAAL 201

  Fly   183 EWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQ-NEAPA 246
            :||||||.||.|||.:||:|||||||.||.||..:..:..|||:||.:||||.||.:.. |..|
Zfish   202 QWVQENIHSFGGDPGSVTIFGESAGGISVSLHVLSPLSANLFHRAIAESGTAAMEAIMNVNPLP- 265

  Fly   247 KTRRLAELLG---GGDFGGDSKALLTFLQ-SEKATPTAILANTLKVLSPDERRRHLPFAFKPVVE 307
                :|:.:|   |.|.....|.:...:| ||.......:.|.|             |.|...::
Zfish   266 ----IAQAIGNASGCDISSTKKIVDCLMQKSEVEILKITMENPL-------------FRFGVTID 313

  Fly   308 DSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVL 372
                 .:||.:...||...:. ...:|::.|..                  :|::..::| |.:|
Zfish   314 -----GQFLPRPAAELFQSQQ-FNKVPLMTGVT------------------DDEIGFVLP-NYLL 353

  Fly   373 DPQAPEAQEAASDIRAFFFNGQALSKENM-------------------DNLVDLFSDYHFSMDLQ 418
            .|......:..|.:........||..:::                   |...::..|:.|::..:
Zfish   354 PPDWINGLDLESILPLLTVFNPALQDQSVLELLLNEYLGTSPDRIRIRDGFREMLGDFMFNIPAR 418

  Fly   419 RAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNE--DLRGVAHADDICYLFQMAGDETEMNRD 481
            :....|.  ...:|:|.|...:.      ..:.|.:  ...|..|.|:|.::|.....|..:...
Zfish   419 QTASYHR--DAGAPVYVYEFRHP------PSVLQRKRPSFSGSDHGDEIVFVFGYCFSEGPIGMA 475

  Fly   482 DLMVTE--RLCE----MWANFARDGKPS----PIWKPVKKPHNGEPIQLDCLLIDRELKMCSNPD 536
            :.:..|  .||.    .|.|||..|.|:    ..|     |..|:  :.:.|.|..:.|..::..
Zfish   476 ENLSDEEDELCRTTMAYWGNFAHTGNPNGPGLTSW-----PEFGD--EAEYLSIGLDPKASTDLK 533

  Fly   537 GERMDFWRSMYRRYRSENFE--AVRAKL 562
            |:...|....:.|..||..|  .|..||
Zfish   534 GKHFTFVTQTFPRILSERKEGPVVNTKL 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	169/576 (29%)
ces2b	XP_021326380.1	COesterase	27..539	CDD:306613	169/576 (29%)
		COesterase	553..1065	CDD:306613	4/9 (44%)
		COesterase	1079..1592	CDD:306613

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920