Protein Alignment clt and NLGN3

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_851820.1
• Gene: NLGN3 / 54413
• HGNCID: 14289
• Length: 848
• Species: Homo sapiens
• Alignment Length: 613
• Identity: 166/613 - (27%)
• Similarity: 242/613 - (39%)
• Gaps: 199/613 - (32%)

  Fly    12 TRFCSSMKVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRP----------- 65
            |.|......:||:...:|.          ..:.:||||||.||:||.||..|.|
Human    46 THFGKLRGARVPLPSEILG----------PVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNAT 100

  Fly    66 ------------------LERFQKQELDCSKEGNVSYQRDPFTLEVAGSEDCLFLNVYAP----- 107
                              |..:....||..    .:|.::|       :||||:||||.|
Human   101 HFPPVCPQNIHTAVPEVMLPVWFTANLDIV----ATYIQEP-------NEDCLYLNVYVPTEDVK 154

  Fly   108 --KVKSTRTP-----------------------------------LPVMVWIHGGGFFFGNGNSD 135
              ..:..|.|                                   .||||:||||.:..|.||.
Human   155 RISKECARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNM- 218

  Fly   136 FHFPAKLMEQ--EVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNN 198
              ....::..  .|||:|||||:|.|||||..::...||.||.||..||.||.||||.|.|||..
Human   219 --IDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRR 281

  Fly   199 VTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAK-TRRLAELLGGGDFGG 262
            :|:||...|.|.|.|.|.:.|::.||.:||:|||:|...|.. |..|.| |..||:.:|....
Human   282 ITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAV-NYQPVKYTSLLADKVGCNVL-- 343

  Fly   263 DSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPD---------RFLEQ 318
            |:..::..|:.:.|.         :::..|.:......||.||::....||         .||..
Human   344 DTVDMVDCLRQKSAK---------ELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNY 399

  Fly   319 DIMELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQ-------- 375
            |||               :|.|..|||..|                    ..|:||:
Human   400 DIM---------------LGVNQGEGLKFV--------------------EGVVDPEDGVSGTDF 429

  Fly   376 -------------APEAQEAASDIRAFFFNGQALSKENMD----NLVDLFSDYHFSMDLQRAVEI 423
                         .||.::...:...|.:...| .::|.:    .||.||:|:.:........::
Human   430 DYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA-DRDNPETRRKTLVALFTDHQWVEPSVVTADL 493

  Fly   424 HASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLF--QMAGDETEM-----NRD 481
            ||  :..||.|||.. |...::|.|..:.:     .||.|::.|:|  .|.| .|::     :::
Human   494 HA--RYGSPTYFYAF-YHHCQSLMKPAWSD-----AAHGDEVPYVFGVPMVG-PTDLFPCNFSKN 549

  Fly   482 DLMVTERLCEMWANFARDGKPSPIWKPV 509
            |:|::..:...|.|||:.|.|:   |||
Human   550 DVMLSAVVMTYWTNFAKTGDPN---KPV 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	164/603 (27%)
NLGN3	NP_851820.1	COesterase	36..624	CDD:278561	166/613 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..195		0/24 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..694

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810