Protein Alignment clt and Ces2h

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 596
• Identity: 168/596 - (28%)
• Similarity: 265/596 - (44%)
• Gaps: 131/596 - (21%)

  Fly     6 CGRLIFTRFCSSMKVKVPVK---QGVLVG---RQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPR 64
            ||.|:..| ........|::   .|.::|   ..|.|..|:  :||||:|:|:||||.|||..|.
Mouse    15 CGLLLLLR-VQGQDSTSPIRTTHTGQILGSLIHMKDLDVGV--HSFLGIPFAKPPVGPLRFAPPE 76

  Fly    65 PLERFQKQELDCSKEGNVSYQRD----------------------------PFTLEVAGSEDCLF 101
            |.|.:          |.|   ||                            ||.:    |||||:
Mouse    77 PPEPW----------GGV---RDGTSHPAMCLQDITAMNMQAFKLLKLTLPPFPM----SEDCLY 124

  Fly   102 LNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNS-DFHFPAKLMEQEVIVVTLNYRLGALGFLSLP 165
            ||:|||......:.||||||||||....|..:. |....|.:  :.|:|||:.||||.|||.|..
Mouse   125 LNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYDGSMLAAM--ENVVVVTIQYRLGVLGFFSTG 187

  Fly   166 EEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQ 230
            :|...||.|..||..||.|:|:|||.|.|:|:.||:||.||||:||.....:..::.||..|||:
Mouse   188 DERARGNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGGTSVSSLVVSPMSQGLFRGAIME 252

  Fly   231 SGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERR 295
            ||.|.:..:....:....:.:|.|.|....  ||:||:..|:.:.......:....|::
Mouse   253 SGVALISSLISVSSDVVYQTVANLSGCEQV--DSEALVNCLRGKSEEEIMAINKAFKII------ 309

  Fly   296 RHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYED 360
                    |.:.|..    ||.:...|||...| ...:|.|:|.|:.|...|:..:...:::.:.
Mouse   310 --------PGIVDGI----FLPRHPQELMASAD-FHPVPSIIGVNNDEYGWIIPSSMSMIDSKKG 361

  Fly   361 DLARLVPRNLVLDPQA------PEAQEAASDIRAFFFNGQALSKENM-DN---------LVDLFS 409
            ...::|  ..:|..:|      ||    .||:         |.:|.| ||         ..::..
Mouse   362 MDRQMV--QAILQRRATQMMWPPE----VSDL---------LMEEYMGDNEDPQFLQVQFKEMMK 411

  Fly   410 DYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLFQ--MA 472
            |:.|.:.   |:::....::.:|::||...:   |..:.|..:...:: ..|.|:|.::|:  ..
Mouse   412 DFTFVIP---ALQVAQFQRSHAPVFFYEFQH---RPSFFKDSKPSHVK-ADHGDEILFIFRSFWG 469

  Fly   473 GDETEMNRDDLMVTERLCEMWANFARDGKPS----PIWKPVKKPHNGEPIQLDCL-LIDRELKMC 532
            |.:.:...::.:::.|:.:.||||||...|:    |.|....:  :.:.:|||.. .:.|.||.
Mouse   470 GTQVDFTEEEELLSRRMMKYWANFARQRNPNSEGLPYWPMFDQ--DEQYLQLDTQPAVGRALKT- 531

  Fly   533 SNPDGERMDFW 543
                 .|:.||
Mouse   532 -----RRLQFW 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	162/578 (28%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:395084	162/578 (28%)