Protein Alignment clt and alpha-Est1

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_524269.3
• Gene: alpha-Est1 / 40909
• FlyBaseID: FBgn0015568
• Length: 565
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 195/550 - (35%)
• Similarity: 294/550 - (53%)
• Gaps: 49/550 - (8%)

  Fly    22 VPVKQGVLVG-RQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQ 85
            |..:.|.:.| |::.|.:...|.:|.|:|:|:|||||||||:|:|...:.... ||:.......|
  Fly    35 VCTRDGQVRGHRRRTLYDEEMYFAFEGIPFAQPPVGELRFRAPQPPHPWLGVR-DCTYPRAKPMQ 98

  Fly    86 RDPFTLE-VAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVIV 149
            :. |.|. |.||||||:||||:.:::|.: ||||:|||:||||.||....||:.|...|:|:|:|
  Fly    99 KH-FVLSIVEGSEDCLYLNVYSKRLRSDK-PLPVIVWIYGGGFQFGEAGRDFYSPDYFMQQDVVV 161

  Fly   150 VTLNYRLGALGFLSLPEE--GIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVH 212
            ||.|||:||||||||.:.  .:.||.|||||.:||.|:.:|||.|||||.|:|:.|||||.:|||
  Fly   162 VTFNYRVGALGFLSLADRDLDVPGNAGLKDQVMALRWISQNIAQFNGDPQNITVMGESAGAASVH 226

  Fly   213 LHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAK-TRRLAELLGGGDFGGDSKALLTFLQSEKA 276
            ........:.||||||||||:...||.  ||...: ..|||..||   :.|.......|...:||
  Fly   227 ALMTTEQTRGLFHKAIMQSGSMFCEWA--NEPSGRWAYRLACQLG---YSGSENEKEVFRYLQKA 286

  Fly   277 TPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGS-MPVIMGYN 340
            ..:.:.|..:.::|.:|||:::.|.|.||||...:.|..|.:...|::  .:..|: :|:|:|.|
  Fly   287 PASEMAAQGITLVSQEERRQYVLFPFTPVVEPYITRDCVLPRCHREML--PEAWGNDLPLILGGN 349

  Fly   341 SAEGL----AIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFF----FNGQALS 397
            |.|||    :.:...:..|.|:|    .|:||.:    :....|....|:...|    |:.....
  Fly   350 SFEGLFSYQSTLHDEEHMLSAFE----VLIPREI----REKSTQSHLKDLLRQFKVDNFDDATRG 406

  Fly   398 KENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGR-NLYKKIFQNEDLRGVAH 461
            :...:..:.:.|..||...:.|.|....|....:|.|.||.|..... |.::::...:.:|||:|
  Fly   407 RMEFNECLHILSVKHFWHGIHRTVLARLSHAPATPTYLYRFDVDSPHFNHFRQVMCGKHVRGVSH 471

  Fly   462 ADDICYLF-QMAGDETEMNRDDLMVTERLCEMWANFARDGKPS------PIWKPV--KKPHNGEP 517
            |||:.||| .:..::.:.:..:....:||..||..|||:..|:      ..|:.:  |.|..
  Fly   472 ADDLSYLFYHILANKVDKSSMEYQTIQRLVGMWVAFARNDNPNCPQIGPTTWEALDEKGPQM--- 533

  Fly   518 IQLDCLLIDRELKMCSNPDGERMDFWRSMY 547
                ||.|.::|:....|:.::...|..:|
  Fly   534 ----CLNIGKQLEFIVLPESKQNRIWDRLY 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	193/544 (35%)
alpha-Est1	NP_524269.3	COesterase	31..555	CDD:395084	193/544 (35%)