Protein Alignment clt and alpha-Est3

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 569
• Identity: 194/569 - (34%)
• Similarity: 288/569 - (50%)
• Gaps: 76/569 - (13%)

  Fly    20 VKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSY 84
            ::|....|.::|:|...|.|.||.||..:|||:||||.|||.:|.|:|.: .|.|||:|.|....
  Fly     4 LQVNTTSGPVLGKQCTGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPW-SQPLDCTKPGQKPL 67

  Fly    85 QRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVIV 149
            |.:.::.::.|.||||:|||||.::.|.| |||::|:..||||..|:...:.|.|...|.::|:|
  Fly    68 QFNHYSKQLEGVEDCLYLNVYAKELDSPR-PLPLIVFFFGGGFEKGDPTKELHSPDYFMMRDVVV 131

  Fly   150 VTLNYRLGALGFLSL--PEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVH 212
            ||::||:|.||||||  |..|:.||.|||||.||:||::||...|||||.|||.||||||.:|||
  Fly   132 VTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKNVTAFGESAGAASVH 196

  Fly   213 LHTFARHAKRLFHKAIMQSGTANMEW---VFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSE 274
            .......|:.||||||:|||.....|   ..:|    ...|||..||              ::|.
  Fly   197 YLMLNPKAEGLFHKAILQSGNVLCSWALCTIKN----LPHRLAVNLG--------------MESA 243

  Fly   275 KATPTAILANTLK-----------VLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKD 328
            :....|::.:.|:           :||.:|......|.|.|:||...:....|.....||:.|
  Fly   244 EHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHCALPNHPQELLDK-- 306

  Fly   329 CLGS-MPVIMGYNSAEGL---AIVVKAKQKLEAYEDDLARLVP----RNLVLDPQAPEAQEAASD 385
            ..|: :||:|...|.|||   |.|..|...|.:.:.:...::|    |||   ||| .|:.....
  Fly   307 AWGNRIPVLMSGTSFEGLLMYARVQMAPYLLTSLKKEPEHMLPLDVKRNL---PQA-LARHLGQR 367

  Fly   386 IRAFFFNG---QALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLY 447
            ::...|.|   .|:|.|::....:..|...|...:.:.:.......:.| .|.||.|:......:
  Fly   368 LQETHFGGNDPSAMSPESLKAYCEYASYKVFWHPILKTLRSRVKSSSAS-TYLYRFDFDSPTFNH 431

  Fly   448 KKI-FQNEDLRGVAHADDICYLFQMAGD---ETEMNRDDLMVTERLCEMWANFARDGKP------ 502
            ::: :..:.||||||.||..||:.  ||   :.:.:..:.:..||:.:|..:|||...|
  Fly   432 QRLKYCGDKLRGVAHVDDHSYLWY--GDFSWKLDKHTPEFLTIERMIDMLTSFARTSNPNCKLIQ 494

  Fly   503 -----SPIWKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSM 546
                 :..|||:....     .|:||.|...:||...|:.:::..|.|:
  Fly   495 DQLPRAKEWKPLNSKS-----ALECLNISENIKMMELPELQKLRVWESV 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	192/562 (34%)
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	192/564 (34%)