Protein Alignment clt and alpha-Est5

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001246965.1
• Gene: alpha-Est5 / 40905
• FlyBaseID: FBgn0261393
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 551
• Identity: 199/551 - (36%)
• Similarity: 288/551 - (52%)
• Gaps: 45/551 - (8%)

  Fly    19 KVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVS 83
            ::.:||  |.:.|.::..:....|.||..:|:|:||:||||||:|.|.:.: ...|||:......
  Fly    12 ELTLPV--GQIKGVKRLSLYDDPYFSFEKIPFAKPPLGELRFRAPVPADPW-SGVLDCTHYAEKP 73

  Fly    84 YQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVI 148
            .||...|.|:.|.||||:||||:.::||.: ||||||:|:||.|..|....:.:.|...|.::|:
  Fly    74 TQRGLLTREIEGGEDCLYLNVYSKQLKSEK-PLPVMVYIYGGAFTVGEATRELYGPDYFMTKDVV 137

  Fly   149 VVTLNYRLGALGFLSL--PEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSV 211
            :||||||:..||||||  |...:.||.|||||.|||:||::.|::||||.:|:|:|||||||.|.
  Fly   138 LVTLNYRVDCLGFLSLKDPSLKVPGNAGLKDQVLALKWVKQYISNFNGDDSNITVFGESAGGCST 202

  Fly   212 HLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGG--DSKALLTFLQSE 274
            |........:.||||||..|||.:..|. .|.|.....|||:..|   |.|  |...:|.:||
  Fly   203 HFMMCTEQTRGLFHKAIPMSGTVHNYWA-NNPAEDFAFRLAQQNG---FTGENDDAKVLEYLQ-- 261

  Fly   275 KATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGY 339
             ..|...|.|. .:|:|:.||..|.|||.|.||.....|..:.:..:| |.:.....:.||::|.
  Fly   262 -GVPARDLVNH-NLLTPEHRRNGLLFAFGPTVEAYVGEDCVVPKPPVE-MARDAWSNNFPVMLGG 323

  Fly   340 NSAEGLAI--VVKAKQK-LEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFNGQALSKENM 401
            .|.|||.:  .|.|..| |::...|..||||.::.......|..|.:..:...:|.....|.|.:
  Fly   324 TSFEGLFMYPAVSANLKALDSLSQDPTRLVPVDVRTVSSEKENLEYSQRLMKAYFGYSPPSSELL 388

  Fly   402 DNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGR-NLYKKIFQNEDLR-GVAHADD 464
            .|::|.:|...|.....|......: ..::|.|:||.|:.... |.|:..|..:.:: |||||||
  Fly   389 LNMLDFYSYKIFWHGFNRTFNARLT-YAKAPTYYYRFDFDSPNFNFYRAKFCGDKIKTGVAHADD 452

  Fly   465 ICYLFQMAG----DETEMNRDDLMVTERLCEMWANFARDGKPS-P-----IWKPVKK--PHNGEP 517
            :.|||:.||    |:|..   :....||:..:|..||....|: |     .|||..|  |.....
  Fly   453 LSYLFRNAGSWKLDKTSA---EYRTIERMIGIWTAFAATSNPNCPEIGHLEWKPSTKNDPKRVIN 514

  Fly   518 IQLDCLLIDRELKMCSNPDGERMDFWRSMYR 548
            |..|..:||.       |:.|::..|.::|:
  Fly   515 ISSDVTIIDL-------PEYEKLQIWDNLYK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	197/541 (36%)
alpha-Est5	NP_001246965.1	alpha/beta hydrolases	12..533	CDD:473884	197/544 (36%)