Protein Alignment clt and alpha-Est6

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_524262.1
• Gene: alpha-Est6 / 40902
• FlyBaseID: FBgn0015574
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 582
• Identity: 187/582 - (32%)
• Similarity: 282/582 - (48%)
• Gaps: 72/582 - (12%)

  Fly     6 CGRLIFTRFCSSMK--------------VKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVG 56
            |.|.:..|.|...|              ||:.|  |.:.||:...:.|.|:.||.|:|:|:||:|
  Fly    15 CFRFLILRCCPGFKRFSCQSAGDADSKVVKLSV--GSVKGRRLSGIYGDEFYSFEGIPFAKPPLG 77

  Fly    57 ELRFRSPRPLERFQKQELDCSKEGNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVW 121
            :.||.:.:..:.: ..|||..:|..:..|.|..:.:|.||||||:||||......:..||||||:
  Fly    78 KARFVASQLADPW-NSELDARQERPIPLQMDRRSGKVVGSEDCLYLNVYTKHFNESEPPLPVMVY 141

  Fly   122 IHGGGFFFGNGNSDFHFPAKLMEQEVIVVTLNYRLGALGFLSLP--EEGIHGNMGLKDQRLALEW 184
            |:||.|..|......:.|..||.::|:.|..||||.:|||||:|  :..:.||.||.||.|||:|
  Fly   142 IYGGAFRTGGAVKSKYGPDYLMSRDVVYVLFNYRLCSLGFLSMPSGKLDVPGNAGLHDQLLALQW 206

  Fly   185 VQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTR 249
            |.::|.:|||||.|:||||||||.:|||.......||.|||||||.||:....||   .||....
  Fly   207 VSQHIRNFNGDPQNITLFGESAGAASVHFMMCLPQAKGLFHKAIMMSGSMLSPWV---NAPDSDG 268

  Fly   250 RLAELLGGGDFGGDSK--ALLTFLQSEKATPTAILANTLKVLSPD---ERRRHLPF--AFKPVVE 307
            ....|.....:.|.::  .:|.||::         .|..|::..|   .|.|...|  .|.|||
  Fly   269 IFCRLATSAGYEGPAEEVPILEFLRN---------VNAEKLIGHDFISPRDRCFGFLNPFAPVV- 323

  Fly   308 DSSSPDRFLEQDIMELMHKK-DCLGSMPVIMGYNSAEGLAIV----VKAKQKLEAYEDDLARLVP 367
                 ...:.....:||.:. .|  .:|:::|..|.|||...    :.....||..:.:.|.::|
  Fly   324 -----GGLVAAPFQQLMKEAWSC--EVPLLLGGTSFEGLVYYPFCQLDNGYMLELLKHEPAMVLP 381

  Fly   368 RNLVLDPQAPEAQEAASDIRAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSP 432
            ..|.......|...||..:..:.:..:.::|.|:..::||||...|...:.|.|....| ..|:|
  Fly   382 HELYQSMSVEERNTAADVLVKYHYGPRGITKSNITQILDLFSYKLFWHGIHRVVLSRLS-HAQAP 445

  Fly   433 LYFYRLDYVGGR-NLYKKIFQNEDL-RGVAHADDICYLF-QMAGDETEMNRDDLMVTERLCEMWA 494
            .|.||.|:...: ||.:.....:|: |||.||||:.|:| :.|..:..::..:.:..:|:..:..
  Fly   446 TYLYRFDFDSPKLNLMRNQLCGDDIKRGVCHADDLGYIFHKQAQAKQPLDSPEFLTIQRMVGILT 510

  Fly   495 NFARDGKPS-------PIWKPV--KKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMY 547
            .|||.|.|:       | |.||  |.|       ...|.|.::::..:..:.:.:..|..:|
  Fly   511 TFARTGDPNCPETGPDP-WMPVSTKSP-------FKALNIGQQVECVTQVEKDGLKVWNRLY 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	178/546 (33%)
alpha-Est6	NP_524262.1	COesterase	35..534	CDD:278561	176/523 (34%)
		Aes	<133..325	CDD:223730	85/209 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I1478
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I2231
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26925
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	9	8.880