DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment clt and CG9287

DIOPT Version :9

Sequence 1:	NP_536784.1	Gene:	clt / 117300	FlyBaseID:	FBgn0000326	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_609244.1	Gene:	CG9287 / 34194	FlyBaseID:	FBgn0032057	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	144/541 - (26%)
Similarity:	221/541 - (40%)	Gaps:	134/541 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 EYNSFLGVPYAEPPVGELRFRSPRPLERFQ------KQELDCSKEGNV-SYQRDPFTLEVAGSED 98
            |...|:.|.|||||.|..||::|||:|.::      .:::.|....:: |.:|....|:|   ||
  Fly    57 EVLQFVDVRYAEPPTGLHRFKAPRPIEPWEDVMDATAEKIGCPSVVSMDSLRRLDDVLDV---ED 118

  Fly    99 CLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVIVVTLNYRLGALGFLS 163
            ||.:.:..|.|.|.   |||:|:|| |.:.:...||:.. |..|:|::|::||..||||..||||
  Fly   119 CLTMTITTPNVTSR---LPVLVYIH-GEYLYEGSNSEAP-PDYLLEKDVVLVTPQYRLGPFGFLS 178

  Fly   164 LPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKR-LFHKA 227
            ...:.|.||.|..|..|||::|:..|..|.|||:.||:.|:..|.:..||.|.:...:| |||:.
  Fly   179 TKTDEIPGNAGFLDIFLALQFVKHFIKYFGGDPSRVTVAGQVGGAAIAHLLTLSPVVQRGLFHQV 243

  Fly   228 IMQSGTANMEWVFQNEAPAKTRR-------------------LAEL------------------L 255
            |..||:|.|. :|..|.|.|..:                   |.||                  |
  Fly   244 IYHSGSAIMP-IFLEEDPRKHAQEIAKKADCKMVTVRDLNTCLMELTALELLTAFMEHALEKSDL 307

  Fly   256 GGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDI 320
            |.|..||        :|.....|:.:|.            :| |:            |..||.:.
  Fly   308 GIGHTGG--------IQFTIGGPSGVLP------------KH-PY------------DLMLETNF 339

  Fly   321 MELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVP--------------RNLV 371
                       |.|.:.|.....|..::      .|..::|....:|              |..|
  Fly   340 -----------SYPAMGGCPKNAGSRVL------NEIVDNDFEGKIPDDEYNTYNYIDHVIRQTV 387

  Fly   372 LDPQAPEAQEAASDIRAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQ-SP--L 433
               ...:.....|.:...|||...:.....|.|:....|...:::.:..|.:..:...: :|  .
  Fly   388 ---GTDKTMLLTSFVTHDFFNRNLMENGTFDTLIPRLIDVAGTLNHKLPVLLALNMNNKHNPDNT 449

  Fly   434 YFYRLDYVGGRNLYKKIFQNEDLR-----GVAHADDICYLFQMAGDETEMNRDDLMVTERLCEMW 493
            :.|..||.|..|.||::.:..:|:     ||:..|:..|||......|.::|.|..:..|:.|:|
  Fly   450 FLYSFDYAGEFNRYKEMDEETNLQSPFKAGVSLTDEALYLFPYPEHVTRLSRPDQSMAHRMVELW 514

  Fly   494 ANFARDGKP-----SPIWKPV 509
            .||...|.|     ...|.|:
  Fly   515 TNFVISGNPLGSARVGYWPPM 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	144/541 (27%)
CG9287	NP_609244.1	COesterase	31..558	CDD:278561	144/541 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870