Protein Alignment clt and Ces5a

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 552
• Identity: 167/552 - (30%)
• Similarity: 265/552 - (48%)
• Gaps: 85/552 - (15%)

  Fly    27 GVLVGRQKKLVNGLE-YNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQRDPFT 90
            |.:.|:|..::..|| .|.|||:|:|.||:|.|||.:|:|...:.... :.:...||.:|...:.
  Rat    38 GWVQGKQATVLGRLEPVNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLR-EATTYPNVCFQNLEWL 101

  Fly    91 L-----------EVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLME 144
            .           ::..|||||:||:|||...:..:.||||:||.||||..|:. |.|...|....
  Rat   102 FIYQNLLKVHYPKLGVSEDCLYLNIYAPAYANDGSRLPVMMWIPGGGFETGSA-SIFDGSALAAY 165

  Fly   145 QEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGS 209
            ::|::||:.||||..||.:...:...||...:||..||:||:|||..|.|:|::||:||.|||..
  Rat   166 EDVLIVTIQYRLGIFGFFNTQNQHAPGNWAFQDQLAALQWVRENINYFGGNPDSVTIFGGSAGAI 230

  Fly   210 SVHLHTFARHAKRLFHKAIMQSGTANMEWV--FQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQ 272
            |:.....:..:..|||:||||||.|.:..:  |.:|.....:.:|::....  ..|||.||..|:
  Rat   231 SISSLILSPLSAGLFHRAIMQSGVAIIPSLKNFDDELKHGLQVVADVCKCN--VSDSKVLLKCLR 293

  Fly   273 SEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIM 337
            .:         ::|::||..::.:    ||..||:.|     |..::.|||:.:| ...::|.|:
  Rat   294 EK---------SSLELLSLGQKTK----AFTRVVDGS-----FFPEEPMELLSQK-TFKTVPSII 339

  Fly   338 GYNSAE-GLAIVVKAKQKL--EAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFNGQALSKE 399
            |.|:.| |..:.::...::  .:.|.....|:...|.:.||....  .|.|    :|:|:....:
  Rat   340 GVNNQECGYILPMREAPEILFGSNESTALTLIHVLLHIPPQYMHI--VAKD----YFHGKHSLTD 398

  Fly   400 NMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVA--HA 462
            ..|.|:|||.|..|.:........|.  ....|:|||...:      ....|||.....|.  |.
  Rat   399 IRDTLLDLFGDVFFVVPGLVTARNHR--DAGGPVYFYEFQH------RPNCFQNTRPAFVKADHT 455

  Fly   463 DDICYLFQ---MAGDET---EMNRDDLMVTERLCEMWANFARDGKPS----PIWKPVKKPHNGEP 517
            |:|.::|.   :.||..   |...|:.:::.::...||||||.|.|:    |:|....:  |...
  Rat   456 DEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFARSGDPNGDDLPLWPAYDQ--NESY 518

  Fly   518 IQLDC------LLIDRELKMCSNPDGERMDFW 543
            ::||.      .|.||           |::||
  Rat   519 LKLDVNISTGWRLKDR-----------RVEFW 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	165/550 (30%)
Ces5a	NP_001012056.2	COesterase	29..539	CDD:395084	165/550 (30%)