Protein Alignment clt and Ces1dl1

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001013911.1
• Gene: Ces1dl1 / 291863
• RGDID: 1359640
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 560
• Identity: 166/560 - (29%)
• Similarity: 249/560 - (44%)
• Gaps: 105/560 - (18%)

  Fly    45 FLGVPYAEPPVGELRFRSPRPLE--RFQKQELD----CSKE---GNV-----SYQRDPFTLEVAG 95
            |||:|:|:.|:|.|||..|:|.|  .|.|....    ||::   |.|     :.:::...|:.
  Rat    50 FLGIPFAKSPLGSLRFAPPQPAESWNFVKNTTSYPPMCSQDAVGGQVLSELFTNRKENIPLQF-- 112

  Fly    96 SEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVIVVTLNYRLGALG 160
            |||||:||||.|...:..:.|||||||||||...| |:|.:...|....:.|:|||:.||||..|
  Rat   113 SEDCLYLNVYTPADLTKNSRLPVMVWIHGGGLVVG-GSSTYDGQALSAHENVVVVTIQYRLGIWG 176

  Fly   161 FLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFH 225
            |.|..:|...||.|..||..||.|||:|||:|.|:|.:||:|||||||.||.:...:..||.|||
  Rat   177 FFSTGDEHSQGNWGHLDQLAALHWVQDNIANFGGNPGSVTIFGESAGGFSVSVLVLSPLAKNLFH 241

  Fly   226 KAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKA---LLTFLQSEKATPTAILANTLK 287
            :||.:||      |..|.|...|              |||.   |:..|...|.|.:|::.:.|:
  Rat   242 RAISESG------VSLNTALITT--------------DSKPIANLIATLSGCKTTTSAVMVHCLR 286

  Fly   288 VLSPDE-----RRRHL-----------PFAFKPVVED----SSSPDRFLEQDIMEL------MHK 326
            ..:.||     .:.:|           .:.|.|.|.|    |.:|:..|.:.....      ::|
  Rat   287 QKTEDELLETSLKLNLFKLDLFGNPKESYPFLPTVIDGVVLSKTPEEILAEKSFNTVPYIVGINK 351

  Fly   327 KDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFF 391
            ::....:|::|||..:||     |..||  .....|.:..|...:.:...|.|.|.       :.
  Rat   352 QEFGWIIPMLMGYPLSEG-----KLDQK--TANSLLWKSYPTLKISEKMIPMASEK-------YL 402

  Fly   392 NGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDL 456
            .|.....|..|...||.:|..|.:........|.  ...:|.:.|..:|   |..:....:.:.:
  Rat   403 GGTDDPAERKDLFKDLVADVIFGVPSVMVSRSHR--DAGAPTFMYEFEY---RPSFVSAMRPKTV 462

  Fly   457 RGVAHADDICYLFQMAGDETEMNRDDLMVTERLCEMWANFARDGKPS----PIWKPVKKPHN--- 514
            .| .|.|:|..:|.....:...:.::..:::.:.:.||||||:|.|:    |.|....:...
  Rat   463 IG-DHGDEIFSVFGSPFLKDGASEEETNLSKMVMKYWANFARNGNPNGGGLPHWPEYDQKEGYLK 526

  Fly   515 -GEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRRYRSE 553
             |...|....|.|:|:.           ||..:..:..:|
  Rat   527 IGASTQAAQRLKDKEVA-----------FWSELKAKEAAE 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	163/548 (30%)
Ces1dl1	NP_001013911.1	COesterase	22..545	CDD:395084	163/548 (30%)