Protein Alignment clt and cest-9.2

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_741910.3
• Gene: cest-9.2 / 259729
• WormBaseID: WBGene00007695
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 130/600 - (21%)
• Similarity: 240/600 - (40%)
• Gaps: 164/600 - (27%)

  Fly    31 GRQKKLVNGLEYNS----FLGVPYAEPPVGELRFRSPRPLERFQKQELDCSK--EGNVSYQRDPF 89
            ||.:.:....:.|:    |..||:|:||:|:|||..|:..:.: ...||.||  ...:|......
 Worm    29 GRVRGITEWSDDNNHKYMFKSVPFAKPPIGKLRFAPPQYPDSW-SGVLDASKYSPACLSNSSTTS 92

  Fly    90 TLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFP-----AKLMEQEVIV 149
            |.:...|||||::|::..: |..|:...|:|:.|||.:   ||:|...||     .:.:.::||:
 Worm    93 TPQEHVSEDCLYINIFTSE-KCLRSKCAVIVYFHGGAY---NGDSATMFPDNFILERYVAEDVIL 153

  Fly   150 VTLNYRLGALGFLSL-PEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHL 213
            .....|||..|.|.. |...:..|:.:.|...||::|...|.:|.|||..||:.|.|:||:.|..
 Worm   154 AIPGVRLGVFGQLYFGPSALLTENLFMFDAVQALDFVHNEIPNFGGDPKQVTIMGHSSGGTLVEA 218

  Fly   214 HTFARHAK---RLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLT-----F 270
            ..|:....   :||.:.|:.|||.                   :.|..|...|:..:::     |
 Worm   219 LGFSNSVDPDLKLFQQIIVLSGTG-------------------MFGFYDLLVDNSFIISEKLGCF 264

  Fly   271 LQSEKATPTAILANTLKVLSPDE------RRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDC 329
            ..:::....|.:|..|:.:...:      .::|:                   :|:.:|..|...
 Worm   265 NGTQEERTDANIAEILECMRQIDGHEIVGMQKHM-------------------EDVYKLTFKSLL 310

  Fly   330 LGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAF----- 389
            .|              |..::...|:|.:.:..:   |||.:.   .....|..:::..:
 Worm   311 RG--------------APFMELNGKIEKFRNSTS---PRNAIF---GTTEYEFRNEVERYLYITT 355

  Fly   390 ----FFNGQALSK-------ENMDNLVD------LFSDYHFSMDLQRA-VEIHASCQTQSPLYFY 436
                |.|..|:::       :|||.:::      ..|...||..:..| .:::.....|.|..|:
 Worm   356 TFLDFENPVAVAQHFDDELMQNMDTMINGDAVSIFVSAAAFSSAMANAGADVYLFETRQWPYSFH 420

  Fly   437 RLD---YVGGRNLYKKIFQNEDLRGVAHADDICYLFQMAGDETEMNRDDLMVTERLCEMWANFAR 498
            ..|   ::|   :::::....|:       ||...|                   ..::..||.:
 Worm   421 VSDMQYFIG---IHREVLHTHDM-------DILDSF-------------------YSKLLVNFTK 456

  Fly   499 DGKPSPIW---KPVKKPH--------NGE-PIQLDCLLIDRELKMCSNPDGERMDFWRSMYRRYR 551
            .|.|||.|   :|.|..:        ||: |:.|:. ..|:|:....   |:.||:.|::.:..:
 Worm   457 TGAPSPEWNSLEPEKMNYLELRVDTRNGKGPVMLEG-YHDKEVSFWY---GDMMDYDRNITKMRQ 517

  Fly   552 SENF----EAVRAKL 562
            |:..    :.|.::|
 Worm   518 SKGLPRENQGVESQL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	126/575 (22%)
cest-9.2	NP_741910.3	alpha/beta hydrolases	22..501	CDD:473884	123/564 (22%)