Protein Alignment clt and Ces1a

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001013786.2
• Gene: Ces1a / 244595
• MGIID: 3648919
• Length: 563
• Species: Mus musculus
• Alignment Length: 576
• Identity: 174/576 - (30%)
• Similarity: 255/576 - (44%)
• Gaps: 104/576 - (18%)

  Fly    22 VPVKQGVLVGRQKKLVNGLE-YNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQ 85
            |...||.::|:...|....: ...|||||:|:||:|.|||..|:|.|.:.      |.:...||.
Mouse    26 VDTLQGKVMGKYISLEGSAQPVAVFLGVPFAKPPLGPLRFAPPQPAETWS------SVKNTTSYP 84

  Fly    86 -------------RDPFTLEVAG-----SEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNG 132
                         .|.||.::..     |||||:||:|:|...:::..||||||:||||...| |
Mouse    85 PMCSQITGVGPVLSDVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSG-G 148

  Fly   133 NSDFHFPAKLMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPN 197
            .|.|...|....:.|::|.:.||||..||||..:|...||.|..||..||:|||.|||:|.|||:
Mouse   149 ASTFDGLALSTHENVVIVVIQYRLGIWGFLSTGDEHSRGNWGHLDQVAALQWVQNNIANFGGDPS 213

  Fly   198 NVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAE--LLGGGDF 260
            :||||||||||.||.:...:...|.||.:||.:||.|....:|:.    .|||.||  .:..|..
Mouse   214 SVTLFGESAGGESVSVLVLSPLTKNLFQRAISESGVALTPCLFRE----TTRRAAEQVAIATGCV 274

  Fly   261 GGDSKALLTFLQSEKATPTAILANTLKV------LSPDERRRHLPFAFKPVVEDS----SSPDRF 315
            ...|..::..|:.:  |...:||.|||:      |..|.|.   .:.|...|.|.    .:|:..
Mouse   275 ATTSADIVHCLREK--TEEELLATTLKMKFFALDLLGDPRE---SYPFLTTVIDGVVLPKAPEEI 334

  Fly   316 LEQDIMEL------MHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDP 374
            |.:.....      ::|::....:|::|||..:||     |..||  :....|.:..|...:...
Mouse   335 LAEKSFNTVPYIVGINKQEFGWFIPMMMGYPLSEG-----KLDQK--SATSLLWKSYPLTNISKE 392

  Fly   375 QAPEAQEAASDIRAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLD 439
            ..|.|.|.       :..|.....:..|..:|:..|..|::........|.  ...:|.|.|...
Mouse   393 LTPVATEK-------YLGGSDCPDKKKDLFLDMMGDVLFAVPSVIVARYHR--DAGAPTYMYEFK 448

  Fly   440 YVGGRNLYKKIFQNEDLRG----VAHADDIC------YLFQMAGDETEMNRDDLMVTERLCEMWA 494
                   |...|.: |:|.    ..|.|::.      :|.:.|.:| |:|...:|:     :.|.
Mouse   449 -------YHPSFVS-DMRPKTVIADHGDEVYSVWGTPFLKEGASEE-EINLSTMMM-----KFWG 499

  Fly   495 NFARDGKPS----PIWKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSM 546
            ||||:|.|:    |.|     |..||  :...|.|....:.......:.:.||.|:
Mouse   500 NFARNGNPNGEGLPHW-----PEYGE--KESYLQIGATTQQAQRLKDKEVAFWTSL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	171/571 (30%)
Ces1a	NP_001013786.2	COesterase	22..545	CDD:395084	171/571 (30%)