Protein Alignment clt and Ces2b

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 559
• Identity: 168/559 - (30%)
• Similarity: 266/559 - (47%)
• Gaps: 109/559 - (19%)

  Fly    43 NSFLGVPYAEPPVGELRFRSPRPLERFQ------------KQELDCSKEGNVSYQRDPFTLEVAG 95
            ::|||:|:|:||||.|||..|...|.:.            .|.|...||  :..:..|    |:.
Mouse    58 HTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTAHPAMCLQNLGVMKE--IKLKLPP----VST 116

  Fly    96 SEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLME--QEVIVVTLNYRLGA 158
            |||||:||:|.|......:.|||||||||||...|..:.   :...|:.  ::::|||:.||||.
Mouse   117 SEDCLYLNIYTPAHAHEGSNLPVMVWIHGGGLVAGMASM---YDGSLLAAIEDLVVVTIQYRLGV 178

  Fly   159 LGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRL 223
            |||.|..::...||.|..||..||.|:|:|||.|.|.|:.||:|||||||:||..|..:..:|.|
Mouse   179 LGFFSTGDQHARGNWGFLDQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSVSSHVVSPMSKGL 243

  Fly   224 FHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKV 288
            ||.|||:||.|.:.::..:.:...:..:|:|  .|....||:||:..|:. |:....:..|.|..
Mouse   244 FHGAIMESGVALLPYLITDTSEMVSTTVAKL--SGCEAMDSEALVRCLRG-KSEAEILAINKLVQ 305

  Fly   289 LSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGS-----MPVIMGYNSAE---GL 345
            :.|            .||:....|           .|.|:.|.|     :|.|:|.|:.|   .:
Mouse   306 MIP------------AVVDGEFFP-----------RHPKELLASEDFHPVPSIIGVNNDEFGWTI 347

  Fly   346 AIVVKAKQKLEAYEDDLARLVPRN----LVLDPQAPEAQEAASDIRAFFFNGQALSKENMD-NLV 405
            .:|:.:.|.::....:..:.|.:|    |:|.|:       .||:....:.|.....:.:. ...
Mouse   348 PVVMGSAQTIKEITRENLQAVLKNTTAQLMLPPE-------CSDLLMEEYMGDTEDAQTLQIQFT 405

  Fly   406 DLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLR----GVAHADDIC 466
            ::..|:.|.:.   |:::....::.:.:|||...:        :|...:|:|    ...|||:|.
Mouse   406 EMMEDFMFVIP---ALQVAYFQRSHASVYFYEFQH--------QIASLKDVRPTHVKADHADEIP 459

  Fly   467 YLF-----QMAGDETEMNRDDLMVTERLCEMWANFARDGKPS----PIWKPVKKPHNGEPIQLDC 522
            ::|     .|..|.||   .:.:::.|:.:.||||||.|.|:    |.| || ..|:.:.:|||.
Mouse   460 FVFGYFFWDMKLDFTE---GEKLLSRRMMKYWANFARHGNPNSEGLPYW-PV-MDHDEQYLQLDT 519

  Fly   523 L-LIDRELKMCSNPDGERMDFWRSMYRRYRSENFEAVRA 560
            . .:.|.||      ..|:.||    .:..|:..:.:||
Mouse   520 QPAVGRALK------SRRLQFW----TKTLSQKIQELRA 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	163/540 (30%)
Ces2b	NP_937814.1	COesterase	32..535	CDD:395084	163/540 (30%)