Protein Alignment clt and cest-28

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_504691.2
• Gene: cest-28 / 187305
• WormBaseID: WBGene00019654
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 600
• Identity: 160/600 - (26%)
• Similarity: 245/600 - (40%)
• Gaps: 173/600 - (28%)

  Fly    35 KLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQRDPFTLEVAGSED- 98
            |.|:|     :||:|:|:|.|   ||:.|.|...:::.. ||:|.|....|..||...:...:|
 Worm    34 KTVDG-----YLGIPFAKPLV---RFKKPEPAGTWEEVR-DCTKYGPRCPQSGPFAEAINFQKDD 89

  Fly    99 ------CLFLNVYAPKV---KSTRTPLPVMVWIHGGGFFFGNGNS--DFHFPAKLMEQEVIVVTL 152
                  ||.|||:: |:   |:.....||||:|||||:.......  |:.....|..::|:||||
 Worm    90 IPDEANCLTLNVFS-KISDSKNFNKTRPVMVYIHGGGYECSASRDYCDYSVAGTLPLKDVVVVTL 153

  Fly   153 NYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFA 217
            |||:|.|||.:..:....||..|.|..|.|.|:|::|.||.|||.|:|:||:|||.:.|.|...:
 Worm   154 NYRVGILGFFTTGDTVCPGNFALWDLTLGLNWIQKHIESFGGDPGNITIFGQSAGAACVDLLALS 218

  Fly   218 RHAKRLFHKAIMQSGTANMEWVFQ--NEAPAKTRRLAELLGGGDFGGDSKALLTFLQS------E 274
            .|::.||::.|:.||.|..|:..:  |.........|..||..  |.:|:.|..:::|      |
 Worm   219 PHSRDLFNRVIVMSGGALCEYAVRTANSQAKVCYEFARHLGYD--GTNSQTLFNWMKSKPLEEIE 281

  Fly   275 KATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMEL---MHKKDCLGSMPVI 336
            |.....:.|:.:             .|:.|.::|.     |..:.:.||   ..|||      ::
 Worm   282 KMNGFQVPASGI-------------LAWTPNLDDD-----FFPKSLDELRIGAPKKD------IM 322

  Fly   337 MGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAP-EAQEAASDIRAFFFNGQALSKEN 400
            ||:...|||..                    ..|:.||..| ||.:        .:..:...|:.
 Worm   323 MGFAEHEGLFF--------------------EFLIKDPTPPLEALK--------LYVNEYYKKDT 359

  Fly   401 MDNLVDLFSDYHFSMDLQRAVEIHA-------SCQTQSPLYFYRLDYVG---------------- 442
            .|         ||.....:.:|.::       ...|:..|    :|:||
 Worm   360 GD---------HFEATRNKIIEFYSRNVEDTDEKSTKERL----IDFVGDALFTAGVFDNAKNCL 411

  Fly   443 --GRNLYKKIF----------QNEDLRGVA--HADDICYL--------FQMAGDETEMNRDDLMV 485
              |.|::..||          |.|.:..||  |..|:.|:        ||...:|.:|
 Worm   412 KHGNNVWLYIFDYCNPSGFGNQEEFMTFVAPTHCTDLRYVLGEGLYSDFQPTEEEHKM------- 469

  Fly   486 TERLCEMWANFARDGKP----SPIWKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSM 546
            .|::..:::|||:.|.|    |..|         |...||   ..|.....|.|.|:    .|:.
 Worm   470 IEKMTTIYSNFAKYGNPNEHGSSEW---------EKFTLD---NPRRHFQISYPRGK----MRND 518

  Fly   547 YRRYRSENFEAVRAK 561
            |...|.:..|.:|||
 Worm   519 YHPDRMKFLELIRAK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	153/580 (26%)
cest-28	NP_504691.2	COesterase	17..516	CDD:278561	153/581 (26%)
		Aes	<112..>222	CDD:223730	47/109 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820