Protein Alignment clt and cest-30

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_504407.1
• Gene: cest-30 / 181871
• WormBaseID: WBGene00015071
• Length: 578
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 155/555 - (27%)
• Similarity: 250/555 - (45%)
• Gaps: 104/555 - (18%)

  Fly     1 MLLRPCGRLIFTRFCSSMKVKVPVKQGVLVGRQ-KKLVNGLEYNSFLGVPYAEPPVGELRFRSPR 64
            :|..|||               |::..:...:. .|:|:|     :||:|:|:.|||.|:|:.|.
 Worm    33 ILNAPCG---------------PIRGNIYKHKNGTKIVDG-----YLGIPFAKAPVGALKFKKPV 77

  Fly    65 PLERFQKQELDCSKEGNVSYQRDPFTLEVAGS------EDCLFLNVYAPKVKSTRTP--LPVMVW 121
            ..|::.:.. ||.:.|....|...|....|.|      |:||.|||:||:.|....|  |||:|:
 Worm    78 AAEKWTEPR-DCYEYGPGCPQTGRFAALTAKSTAAFAEENCLTLNVFAPRWKLAEFPKGLPVLVY 141

  Fly   122 IHGGGFFFG--NGNSDFHFPAKLMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEW 184
            |:|||:..|  :...|:.....|..::|||||:|||||.||||::.:...:||.||.||.|||:|
 Worm   142 IYGGGYEIGFTSYMDDYSLTGTLPLKDVIVVTMNYRLGPLGFLTIADGIANGNYGLWDQTLALQW 206

  Fly   185 VQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVF--QNEAPAK 247
            ||:|||||.|:|.:|||.|.|||.:|....:.:.|:.:||.::|..||||...:..  ::.....
 Worm   207 VQDNIASFGGNPESVTLSGTSAGATSTDFLSLSPHSNQLFQRSISMSGTAFCNFAIRPKDVEVGV 271

  Fly   248 TRRLAELLGGGDFGGDSKALLTFLQSE---KATPTAILANTLKVLSPDERRRHLPFAFKPVVEDS 309
            .:..|:.  .|..|.||::|..:..::   |....|...:|.....|          |.|..:..
 Worm   272 CKEFAQF--QGYTGTDSQSLFDWYMAQNVSKFKEVAGFQSTAAGAVP----------FIPNFDGD 324

  Fly   310 SSPDRFLEQDIMEL-MHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLD 373
            ..|..|   ||:.. ..|||.|  :.|:    :.|.:.:::.......||.:.      ...:.:
 Worm   325 FFPKPF---DILRREAPKKDAL--ITVV----TMESVGMIIFNPLFANAYNNF------EGFINE 374

  Fly   374 PQAPEAQEAASDIR----AFFFNGQALSKENMDN--LVDLFSDYHFSMDLQRAVEIHASCQTQSP 432
            ...|:..:..:|::    .|:......|.:...|  :||..||..|:.....||:.:..
 Worm   375 TYGPDVTDYYADVKKKLTGFYLKDVNASDKATVNRRVVDYVSDSVFNSGTLDAVKSYVK------ 433

  Fly   433 LYFYRLDYVGGRNLYKKIFQN-----EDLRGVAHADDICYLF------QMAGDETEMNRDDLMVT 486
             |..:: |:|..|.:....::     :..:..:|:.|..|.|      .....:.||...|:..|
 Worm   434 -YGNKV-YLGSFNYFNDATKDMVELMQPFKEASHSSDFKYYFGSGVMANFTPTDEEMEVMDMSGT 496

  Fly   487 ERLCEMWANFARDGKPS------PIWKP--VKKPH 513
                 :.|||.:.|.|:      | |||  :.||:
 Worm   497 -----LMANFVKYGDPNGKSGTKP-WKPYTILKPN 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	151/534 (28%)
cest-30	NP_504407.1	COesterase	30..547	CDD:395084	155/555 (28%)