Protein Alignment clt and cest-13

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_741921.1
• Gene: cest-13 / 181493
• WormBaseID: WBGene00010116
• Length: 548
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 141/543 - (25%)
• Similarity: 233/543 - (42%)
• Gaps: 102/543 - (18%)

  Fly    37 VNGLEY---NSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQRDPFTLEVAGSED 98
            :.|:::   .||.|:.||:||||..||.:.|.|:....  ::....||:..|.|..|    ..||
 Worm    36 IRGIQHTYGTSFRGIRYAQPPVGLFRFGAARRLDPVGL--VEAQAYGNICVQGDGRT----SHED 94

  Fly    99 CLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFH-FPAKLMEQEVIVVTLNYRLGALGFL 162
            |||:|||.|...:..:.|||.|:||||||..|.||.... :|..:.:..:::|::|||||..||.
 Worm    95 CLFINVYTPNNVTQASKLPVYVYIHGGGFVEGGGNMGAGIYPNLVNKGPIVMVSINYRLGPFGFF 159

  Fly   163 SLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKA 227
            |..:....||..:.|...||.|||..|:.|.||||.||:.|:|:|..:|...|....||.||.::
 Worm   160 STRQMTAPGNWAISDWIEALNWVQRYISFFGGDPNRVTIGGQSSGAEAVSTLTLTPLAKNLFKQS 224

  Fly   228 IMQSGTANMEWV--FQNEAPAKTRRLAELLG---------GGDFGGDSKALLTFLQSEKATPTAI 281
            |.:||:|....|  :..:..:.:::|:..||         |..||    .:||.|::........
 Worm   225 IHESGSAFGAAVMSYSEKTRSTSKQLSIKLGCATSDQWDNGQSFG----TILTCLRNVTYDKIVA 285

  Fly   282 LANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMG-------- 338
            ..|:|    |..|.:.      .:|:|    :::|.|.:..|..::|  ....|::|
 Worm   286 ADNSL----PGHRMKW------SIVQD----NKYLTQRLEYLALQRD--PKKNVLIGDVHDEWLG 334

  Fly   339 -------------YNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFF 390
                         :|:|..:...:....::..:::..:.||                |:|.:  :
 Worm   335 WEMNNVLHNINSSHNTAHQMRDDLSGSYEMTYWDNKQSVLV----------------AADNK--Y 381

  Fly   391 FNGQALSKEN----MDNLVDLFSDYHF-SMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKI 450
            .|.|..:.:|    ....:.|:|:..| ...|:.|....   ..::.:|.|.||::....|  .:
 Worm   382 INNQGWTDDNHREWEARRIQLWSEMVFIGPTLRDAAYFQ---YMKNNVYLYSLDWLSPPAL--PL 441

  Fly   451 FQNEDLRGVAHADDICYLFQMAGDETEMNRDDLMVTERLCEMWANFARDGKPSPIWKPVKKPHNG 515
            ..:...||..|..::.|:|..:.:.......|.::.......|.||...|.|:|.         |
 Worm   442 VTDPLFRGCEHTWELQYIFSTSCNGFTCTAQDEILRNYFTTTWLNFIIGGNPTPA---------G 497

  Fly   516 EPIQLDCLLID---RELKMCSNP 535
            .|:....|.:|   |.|....||
 Worm   498 SPLPFKWLAMDSTNRFLSFSPNP 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	141/543 (26%)
cest-13	NP_741921.1	alpha/beta hydrolases	24..526	CDD:473884	141/543 (26%)