Protein Alignment clt and cest-3

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 539
• Identity: 119/539 - (22%)
• Similarity: 205/539 - (38%)
• Gaps: 128/539 - (23%)

  Fly    10 IFTRFCSSMKVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSP------RPLER 68
            :||...|..:: :....|.|.|   |.|| ::.:.|..||:|:||:|:|||..|      :.:..
 Worm    13 VFTLNGSGQRI-ISTTYGKLEG---KTVN-VDQHMFKNVPFAKPPLGKLRFSLPEWTNPWKNIRN 72

  Fly    69 FQKQELDCSKEGNVSYQRDPFTLEVAGSEDCLFLNV----YAPKVKSTRTPLPVMVWIHGGGFFF 129
            ..:....|....::....:.|.:    |||||:|||    |..|.|:..|    :|:.||||.
 Worm    73 ATEYSPSCFSNSSMRTDSNFFPM----SEDCLYLNVFTNEYCLKSKNCST----VVYYHGGGI-- 127

  Fly   130 GNGNSDFHFP-----AKLMEQEVIVVTLNYRLGALGFLSLPEEG-IHGNMGLKDQRLALEWVQEN 188
             |.:|...|.     .:.:::.|:.:...||||..|.|...... :..|:.:.|..|||.::.:.
 Worm   128 -NMDSAVQFNDTFILERYVKENVVFIIPAYRLGIFGLLYFGSNNLVPQNLAIHDCELALRFIHQE 191

  Fly   189 IASFNGDPNNVTLFGESAGGSSVHLHTFARHA---KRLFHKAIMQSGTANMEWVFQNEAPAKTRR 250
            |::|.|..:::.|.|.|||.....:..|:||.   .:|.::.|:.|             |..:..
 Worm   192 ISNFGGHKDDINLMGHSAGAHISLIFGFSRHIDPDHKLINRIIVLS-------------PVPSYD 243

  Fly   251 LAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRF 315
            :.|||        .|....|.:........:.|.
 Worm   244 MPELL--------IKNCYDFAERVGCYKRNVTAR------------------------------- 269

  Fly   316 LEQDIMELMHKKDCLGSMPV--------IMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVL 372
             :.:|::.:.|||..|.|.:        :..:|...|...:.:.    |:..|.....|.|::::
 Worm   270 -DTEIVKCLRKKDARGLMSMQRLMENDRLYFWNFLAGEPFMYRD----ESIADFKEYAVKRDMLI 329

  Fly   373 DPQAPEAQEAASDIRAFFFNGQALSKEN-------MD-----NLVDLFSDYHFSMDLQRAVEIHA 425
            .....|.:            .:.|.|||       ||     .:...|:.||.|..:....|...
 Worm   330 GNTVDEVK------------WKRLKKENPAIAGSFMDWENPYEVAHKFNFYHDSAPVNSTYESFT 382

  Fly   426 SCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLFQMAGDETEMNRDDLMVTERLC 490
            .....|...:.......|..:|  :||:.. :..:|..|:.|......::...:..|:|.| ...
 Worm   383 QGIFVSTATYAEAQANAGGTVY--LFQSNQ-QPSSHVSDMQYFVGTHREDYHTSDMDIMDT-FYS 443

  Fly   491 EMWANFARDGKPSPIWKPV 509
            :|..||.:.|.|||:|:|:
 Worm   444 KMIVNFTKFGSPSPVWEPL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	116/527 (22%)
cest-3	NP_510042.2	Abhydrolase	23..496	CDD:304388	116/529 (22%)
		Aes	<118..>254	CDD:223730	40/163 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900