Protein Alignment clt and cest-16

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 173/646 - (26%)
• Similarity: 279/646 - (43%)
• Gaps: 156/646 - (24%)

  Fly    24 VKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQ--- 85
            |:||::.|.... ::|.....|.||||||||:|||||:.|....|:. |||...:.|....|
 Worm    28 VEQGLVRGNIYN-IDGKHIQIFRGVPYAEPPIGELRFKPPVKKTRWH-QELPAVEYGPPCLQFMD 90

  Fly    86 ---RDPF--TLEVAGSEDCLFLNVYAP-KVKSTRTPLPVMVWIHGGGFFFGNGNSDFH---FPAK 141
               .|.|  |.....|||||:|||::| .........|::||||||.|..|:.::...   ..|.
 Worm    91 FHKNDKFAKTNMDRQSEDCLYLNVFSPYDTDDESKTYPILVWIHGGSFLAGSADTGIDMEVIAAN 155

  Fly   142 LMEQEVIVVTLNYRLGALGFLSLPE-EGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGES 205
            ::.:.:..|::|||||.|||::... :.:.||.|:.|..:||:|:|.||..|||||..||:.|||
 Worm   156 IVSKGIAFVSINYRLGPLGFMNYQNGDKLEGNFGIWDMVMALQWIQSNIKQFNGDPTKVTVMGES 220

  Fly   206 AGGSSVHLHTFARHAKRLFHKAIMQSGTANMEW-VFQNEAPAKTRRLAELLGGGDFGGDSKALLT 269
            |||::..|...:.....|.|:||:.||::...| :.::..||             :..|:  |:.
 Worm   221 AGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIHRHSQPA-------------YSVDN--LVA 270

  Fly   270 FLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLE----QDIMELMHKKDCL 330
            :.:.||    .|..:..|.:..|| .:||..:   |:..:....:.::    .|.|..|.|.:||
 Worm   271 YFRCEK----WINEDDTKEVVGDE-YQHLTHS---VIRSALCNYQNVKINCLTDDMTQMDKMNCL 327

  Fly   331 G-----SMPVIMGYNSAE-GLAIVVKAKQKLEAYEDDL-----ARLVPRNLVLDPQAPEAQEAAS 384
            .     |.|:.....:|| |::.:|        .:.||     ..||..|..:......|::...
 Worm   328 RKELNFSSPLFRKALAAELGVSKMV--------VDGDLVPSSGVSLVRNNARIPIMTGVARKEWG 384

  Fly   385 DIRAFFFN-----GQALS--KENMDNLVDLFSDYH------------------------------ 412
            ..:|.|:|     |...|  :|.:..::|  :.:|
 Worm   385 HKKAMFYNMHQRDGLKRSDVEEQVYRIID--NSFHETASEKLANSTVQLIANATIVRYLETPNNE 447

  Fly   413 FSMD--------LQRAVEIHASCQTQ--------SPLYFYRLDYV-------GGRNLY------- 447
            |..|        |:..:|..|.|:.:        .|:|.|..|||       ..|.:|
 Worm   448 FIADQVVGALQKLESDIEFVAPCEREVAAYVDKGVPVYLYSFDYVPKSPILESERKIYSLFGTKP 512

  Fly   448 ---KKIFQNEDLRGVA-HADDICYLFQMA-GDETEMN----RDDLMVTERLCEMWANFARDGKPS 503
               |:..::|.|...| |..|..::|... ....|::    |::.| ::.||.|..||.::|.||
 Worm   513 VEMKRTEKSEILEKAAFHGLDHAFIFSKGYSSNFEISPYTKREETM-SKILCTMLTNFVKNGDPS 576

  Fly   504 PI---WKPVKKPHNGEPIQLD--CLLIDRELKMCSNPDGERMDFWRS---MYRRYRSENFE 556
            ..   | |:...::.:.:.||  ..|::.|:..   ||.:   ||.:   :..||.|::.|
 Worm   577 TTRFSW-PIFSGNSSQYVSLDVPLKLLEGEIHF---PDAQ---FWNTEAELITRYVSKDSE 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	167/628 (27%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	165/616 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010