Protein Alignment clt and cest-26

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 163/590 - (27%)
• Similarity: 267/590 - (45%)
• Gaps: 104/590 - (17%)

  Fly    21 KVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQ 85
            :|..:.|::.|.:.|:.:..|.:.|||:|:|:.|||:|||::|...|.:...: .|.:.|..:.|
 Worm    43 QVRTRNGLVEGFRIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVK-KCVRFGPRAPQ 106

  Fly    86 RD----PFTLEVAGSEDCLFLNVYAP--KVKSTRTPL-PVMVWIHGGGFFFGNG--NSDFHFPAK 141
            .|    .|||.|..|||||:|||::|  |.:.....| ||||::|||||...:.  ..|......
 Worm   107 ADFFWERFTLGVGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVKYGDEGIAKY 171

  Fly   142 LMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESA 206
            |....|:|||:.||||.|||.|..::...||:||.|..:||:||::|:.:|.|||..||:||:||
 Worm   172 LCRHGVVVVTIQYRLGLLGFFSTGDQVCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSA 236

  Fly   207 GGSSVHLHTFARHAKRLFHKAIMQSGTANMEW--VFQNEAPAKTRRLA------ELLGGGDFGGD 263
            ||.||.|.:.:.|::.|||:.:..:|....||  |.:|......|..|      |.....:  ..
 Worm   237 GGVSVDLLSLSPHSRDLFHQVVPMAGNGECEWSTVGKNRLVNACREFAYRKCWDEKQARDE--NA 299

  Fly   264 SKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMH--- 325
            |:::|.||::.|.........|.|  ..|..:..|..|  ||:  .|.|..||.:.|.||..
 Worm   300 SESMLEFLRTRKEREFEKRLLTRK--GVDVSKIGLDLA--PVI--GSKPSDFLPKSIEELRKEAP 358

  Fly   326 KKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRN------------LVLDPQAPE 378
            ||:      :::|....|||.               .|.|.|.|            |:.:....:
 Worm   359 KKN------IMVGTCEHEGLL---------------FASLGPSNFDEKGIDKLLALLITEENHED 402

  Fly   379 AQEAASDIRAFFFNGQALSKENMD------NLVDLFSD-------YHFSMDLQRAVEIHASCQTQ 430
            .:....:.:..:.  :.||.:..|      ..:.|:||       |:::..:.:         ..
 Worm   403 FEALREEAKKMYL--KKLSDDEDDKEVAARGYIQLYSDLFVNNGTYNYAEKMTK---------LG 456

  Fly   431 SPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLFQMA-GDETEMNRDDLMVTERLCEMWA 494
            :.::.|..||...|: :..:......|...|..::.|:|.:: ......|..|..:.:.:.:||.
 Worm   457 NKVFMYSFDYCNPRS-FGILSLRAPFRAATHCTELAYIFGVSIVFNYRYNESDRAMLDLMTKMWT 520

  Fly   495 NFARDGKP------SPI----WKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRR 549
            |||:.|.|      |.:    |:|..|.   ||... ..:.:::.:|.:.....|.:||:.:  :
 Worm   521 NFAKYGNPNGQYEDSTVFDFKWEPTSKE---EPTNF-LAINEKKCEMQTVYQDNRAEFWKKI--K 579

  Fly   550 YRSEN 554
            ..|:|
 Worm   580 ITSKN 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	159/576 (28%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	159/577 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.920