Protein Alignment clt and cest-26

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 578
• Identity: 161/578 - (27%)
• Similarity: 269/578 - (46%)
• Gaps: 80/578 - (13%)

  Fly    21 KVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQ 85
            :|..:.|::.|.:.|:.:..|.:.|||:|:|:.|||:|||::|...|.:...: .|.:.|..:.|
 Worm    43 QVRTRNGLVEGFRIKIDDDREVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVK-KCVRFGPRAPQ 106

  Fly    86 RD----PFTLEVAGSEDCLFLNVYAP--KVKSTRTPL-PVMVWIHGGGFFFGNG--NSDFHFPAK 141
            .|    .|||.|..|||||:|||::|  |.:.....| ||||::|||||...:.  ..|......
 Worm   107 ADFFWERFTLGVGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLIDSAVKYGDEGIAKY 171

  Fly   142 LMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESA 206
            |....|:|||:.||||.|||.|..::...||:||.|..:||:||::|:.:|.|||..||:||:||
 Worm   172 LCRHGVVVVTIQYRLGLLGFFSTGDQVCPGNLGLWDMTMALQWVRDNVHAFGGDPRKVTVFGQSA 236

  Fly   207 GGSSVHLHTFARHAKRLFHKAIMQSGTANMEW--VFQNEAPAKTRRLA------ELLGGGDFGGD 263
            ||.||.|.:.:.|::.|||:.:..:|....||  |.:|......|..|      |.....:  ..
 Worm   237 GGVSVDLLSLSPHSRDLFHQVVPMAGNGECEWSTVGKNRLVNACREFAYRKCWDEKQARDE--NA 299

  Fly   264 SKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMH--- 325
            |:::|.||::.|.........|.|  ..|..:..|..|  ||:  .|.|..||.:.|.||..
 Worm   300 SESMLEFLRTRKEREFEKRLLTRK--GVDVSKIGLDLA--PVI--GSKPSDFLPKSIEELRKEAP 358

  Fly   326 KKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFF 390
            ||:      :::|....|||..........:  |..:.:|:.. |:.:....:.:....:.:..:
 Worm   359 KKN------IMVGTCEHEGLLFASLGPSNFD--EKGIDKLLAL-LITEENHEDFEALREEAKKMY 414

  Fly   391 FNGQALSKENMD------NLVDLFSD-------YHFSMDLQRAVEIHASCQTQSPLYFYRLDYVG 442
            .  :.||.:..|      ..:.|:||       |:::..:.:         ..:.::.|..||..
 Worm   415 L--KKLSDDEDDKEVAARGYIQLYSDLFVNNGTYNYAEKMTK---------LGNKVFMYSFDYCN 468

  Fly   443 GRNLYKKIFQNEDLRGVAHADDICYLFQMA-GDETEMNRDDLMVTERLCEMWANFARDGKP---- 502
            .|: :..:......|...|..::.|:|.:: ......|..|..:.:.:.:||.|||:.|.|
 Worm   469 PRS-FGILSLRAPFRAATHCTELAYIFGVSIVFNYRYNESDRAMLDLMTKMWTNFAKYGNPNGQY 532

  Fly   503 --SPI----WKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRRYRSEN 554
              |.:    |:|..|.   ||... ..:.:::.:|.:.....|.:||:.:  :..|:|
 Worm   533 EDSTVFDFKWEPTSKE---EPTNF-LAINEKKCEMQTVYQDNRAEFWKKI--KITSKN 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	157/564 (28%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	157/565 (28%)