Protein Alignment clt and cest-34

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 160/525 - (30%)
• Similarity: 241/525 - (45%)
• Gaps: 118/525 - (22%)

  Fly    41 EYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQRDPFTLEVAGSEDCLF---- 101
            |.:.:||:|||:||.||:||..|.|.:.:.:.. ||:|.|    .|.|.:.:  |.|..:|
 Worm    35 EVHGYLGMPYAKPPTGEMRFAKPVPADDWTETR-DCTKYG----PRCPPSGQ--GLEKGMFVNPD 92

  Fly   102 ---------LNVYAPKVKST--RTPLPVMVWIHGGGFFFGNGNS--DFHFPAKLMEQEVIVVTLN 153
                     :||:.|..:|:  :...||||::|||||...:...  |:...:.|..::||:||:|
 Worm    93 EPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEISSSREFCDYSISSTLPMKDVILVTMN 157

  Fly   154 YRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHLHTFAR 218
            ||||.|||.:..:|...||.||.||.|||:|||::||||.||||||||||:||||:.|.|.|.:.
 Worm   158 YRLGILGFFTTGDEVCPGNFGLWDQTLALQWVQKHIASFGGDPNNVTLFGQSAGGACVDLLTLSP 222

  Fly   219 HAKRLFHKAIMQSGTANMEWVF---QNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSEKATPTA 280
            |::.||.|.:..||:|..|:..   :|||......||.|   |..|..||..|.|::|
 Worm   223 HSRDLFQKVVPMSGSAMCEFAMRTAENEAHVFDDILARL---GFTGSGSKERLEFMRS------- 277

  Fly   281 ILANTLKVLSPDERRRHLPFAFKPVVEDSSSPD---RFLEQDIMELMHKKDCLGSMPVIM-GYNS 341
                    |..|:......:.:|.....|..|:   .|..:.:.||  :||  .|..::| |...
 Worm   278 --------LPCDKITGKTGYTYKQSGFMSLCPNYDGDFFPKPLDEL--RKD--ASKRILMTGIVG 330

  Fly   342 AEGLAIVVKAKQKLEAYED--DLARLVPRNLVLDPQAPEAQEAASDIRAFFFNGQALSKENMDNL 404
            .|||..   |..:...|:|  ||.|       |..:....::...|:       :.:.||..:..
 Worm   331 NEGLLF---AFDRNTPYKDYTDLLR-------LKIEEDYKEDVVDDV-------EGIRKEIFEYY 378

  Fly   405 VDLFSDYHFSMDLQRAVE----------IHASCQTQS----PLYFYRLDYVGGRNLYKKIFQNED 455
            ....|:......:::|.|          :.|:.|..:    .::.|..||.           |.|
 Worm   379 TKNISEGDEEAIMRKAAEFVGDSIFHTGVRATAQNAAEHGDEVWLYNFDYC-----------NPD 432

  Fly   456 ----LRGV------AHADDICYLFQMAGD----ETEMNRDDLMVTERLCEMWANFARDGKP---- 502
                |:|.      .|..::.|||   ||    :.|...::|.:.::...|:||||:.|.|
 Worm   433 GFAPLKGYLPYIEPTHGMELRYLF---GDGIISKFEPTEEELKMLDKFTTMFANFAKYGNPNETG 494

  Fly   503 SPIWK 507
            |..|:
 Worm   495 SSAWE 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	160/525 (30%)
cest-34	NP_001360105.1	COesterase	15..517	CDD:395084	160/525 (30%)