Protein Alignment clt and cest-10

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 135/608 - (22%)
• Similarity: 221/608 - (36%)
• Gaps: 152/608 - (25%)

  Fly    10 IFTRFCSSMKVKVPVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQ--KQ 72
            :|:..|....|.|....|.|.|.|  :.|   ::.|..:|:|:||:|:|||:.|:|.|.:.  :.
 Worm    12 LFSFSCFVDSVIVETSLGKLNGDQ--IGN---FHLFKKIPFAKPPLGKLRFQKPQPAETWNGVRN 71

  Fly    73 ELD----CSKEGNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGN 133
            ..|    |....:.:.     |::....||||.||::..:.........|::::|||
 Worm    72 AKDYGPACMSNSSTTK-----TVQKWVDEDCLHLNIFTSETCLKSKNCAVVIYLHGG-------- 123

  Fly   134 SDFHFPAKLM-----------EQEVIVVTLNYRLGALGFLSLPEEGI-HGNMGLKDQRLALEWVQ 186
             :.|:.:.:|           .||::.|....|||......:.::.| ..|:.|.|...|:|:.:
 Worm   124 -NLHYDSAVMFNDTFLLHTYASQEIVFVIPAVRLGIFSHFVVEDQSIAPNNLALFDMLQAMEFAK 187

  Fly   187 ENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAK---RLFHKAIMQSGTANMEWV-FQNEAPAK 247
            .:|.:|.|:....||.|.|.||:...:.:|:....   .||.:.|..|...|.:.: .|.|   :
 Worm   188 SDIHNFGGNNKRTTLLGHSYGGTVASMLSFSTKVNTDLSLFQQYISMSSPTNFDTLELQVE---R 249

  Fly   248 TRRLAELLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDER---RRHLPFAFKPVVEDS 309
            |.|.||  .......:||.:      .|......:.:.||..|..|.   :|.|..|..||...|
 Worm   250 TYRFAE--HANCLPKNSKFM------RKNQKEVYMRDCLKKKSASELLRIQRSLEEAGYPVYGGS 306

  Fly   310 --SSP--DRFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAI-----VVKAKQKLEAYEDDLARL 365
              ..|  ...||:|.|      |...::..:.|....|.|..     :.|| ...|.||:
 Worm   307 VMRGPIFQEVLERDFM------DSPNNITSLTGCTKYESLVYDHYRNMGKA-LGFENYEE----- 359

  Fly   366 VPRNLVLDPQAPEAQEAASDIRAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQ 430
                 |.:....:::|...:.            :|:.|...:       |.:|....::...:..
 Worm   360 -----VNEKYRSDSKEGKIEF------------DNVKNATQI-------MLIQIRTRVNKILKKN 400

  Fly   431 SPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLF---QMAGDETEMNRDDLMVTERLCEM 492
            .|.|.|...|....|               |.||:.::.   ....||.|:...:...:     |
 Worm   401 IPAYHYEYAYPKHAN---------------HTDDLFFIMGVHPFIQDENEIKLGNFYRS-----M 445

  Fly   493 WANFARDGKP---------------SPIW------KPVKKPHNGEPIQLD-----CLLIDRELKM 531
            :.||.:.|.|               ...|      :||.| :|.|...||     .:..|||:.:
 Worm   446 FLNFIKTGNPGNGCDGANLNGSTYFEVNWNETTGERPVMK-NNFEQKILDYWTKNMIEFDREVSL 509

  Fly   532 CSNPDGERMDFWR--SMYRRYRS 552
            ..|....|....|  |.|..:.|
 Worm   510 LRNIKSRRQPASRVFSAYYSFMS 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	128/583 (22%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	123/566 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900