Protein Alignment clt and cest-5.2

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_501021.3
• Gene: cest-5.2 / 177428
• WormBaseID: WBGene00015284
• Length: 583
• Species: Caenorhabditis elegans
• Alignment Length: 513
• Identity: 108/513 - (21%)
• Similarity: 197/513 - (38%)
• Gaps: 121/513 - (23%)

  Fly    27 GVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLER----FQKQELDCSKEGNVSYQRD 87
            |.|.|:|..     :|..|..:|:|:||:|.|||:.|...|:    :...|...:...|.::.:.
 Worm    29 GRLEGKQSG-----KYQLFRRIPFAKPPIGTLRFQKPESAEKWNGVWNATEYGPACMSNSTWTQS 88

  Fly    88 PFTLEVAGSEDCLFLNVYAPKVKSTRTPLPVMVWIHGGGFFFGNG---NSDFHFPAKLMEQEVIV 149
            |   :....||||.:|::............|:|:||||...|.:.   |..|...: .::|:||:
 Worm    89 P---QKWVDEDCLHVNIFTSDKCLKSKDCAVVVYIHGGEIVFDSAVMFNDTFLLES-FVKQDVIL 149

  Fly   150 VTLNYRLGALGFLSLPEEGI-HGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGSSVHL 213
            |...:|||.....::.::.| ..|:.|.|..||.|:|:..|.:|.||...:||||.|.||:...:
 Worm   150 VIPAFRLGIFSHFTVHDQNIAPNNLALYDIILAQEFVKSEIHNFGGDIQKITLFGHSYGGTIASM 214

  Fly   214 HTFARHAKR---LFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQSEK 275
            ..|:....:   ||.:.|:.|  ||..:....|...::.|:.:..|                  .
 Worm   215 MAFSSEINQDLSLFQRIIVMS--ANQYFDTLEEQIERSDRVVKHAG------------------C 259

  Fly   276 ATPTAILANTLKVLSPDERRRHLPFAFKPV-----------VEDSSSPD---------RFLEQDI 320
            :.||    |..:.::..::.:::....:.:           :|::..||         .|.:...
 Worm   260 SVPT----NLARKMNRSQKEKYMMKCLQKLSGMELLSVQRSLEEAGYPDIGNLVLRGPLFPDVTS 320

  Fly   321 MELMHKKDCLGSMPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASD 385
            :|::.....:   |::.|..             |.|:.::|....:.::..|:......::...|
 Worm   321 LEMLESPKMI---PMLAGCT-------------KFESDDEDETHFIGKHFGLENPIECDEKYRKD 369

  Fly   386 IRAFFFNGQALSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQS------PLYFYRLDYVGGR 444
            :....|:.|..|                  |..:|:.:....:...      |.|.|...|.
 Worm   370 LENGIFDRQNHS------------------DKTQAIMVPTKLRVDQLRKHGVPAYLYEFTYP--- 413

  Fly   445 NLYKKIFQNEDLRGVAHADDICYLFQMAGDETEMNRDDLMVTERLCEMWANFARDGKP 502
               |..|         |.||:.|:..:...|.:.|.:.|....|  .|..||.:.|:|
 Worm   414 ---KHAF---------HTDDLYYIMGIHPFEKDENEEHLEKVYR--NMLINFIKFGEP 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	108/513 (21%)
cest-5.2	NP_501021.3	alpha/beta hydrolases	21..498	CDD:473884	108/513 (21%)