Protein Alignment clt and cest-27

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 567
• Identity: 170/567 - (29%)
• Similarity: 264/567 - (46%)
• Gaps: 76/567 - (13%)

  Fly    23 PVKQGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRPLERFQKQELDCSKEGNVSYQRD 87
            |:|.   ||.:::  :|.....|||:||||||:|.|||:.| ...|...:.|||.:.|..|.|.|
 Worm    34 PIKG---VGYEQE--DGSVVEGFLGIPYAEPPIGALRFKKP-VAHRKWTEPLDCVRFGPRSPQND 92

  Fly    88 ----PFTLEVAGSED-CLFLNVYAPKVKSTRTP--LPVMVWIHGGGFFFGNGNSDF---HFPAKL 142
                .|...|..||: ||.|||:.||.:|...|  .||||:||||||.. :.:|::   .....|
 Worm    93 ELLGQFVNTVGKSEEHCLSLNVFTPKWESNEWPDGFPVMVFIHGGGFAV-HSSSNYGCASIARNL 156

  Fly   143 MEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAG 207
            ..::|:|||:|||||.|||.:..:|...||:||.||..|||||||||.||.|||:|||:||:|||
 Worm   157 CTKDVVVVTINYRLGVLGFFTTGDEVCRGNLGLWDQTAALEWVQENIQSFRGDPDNVTIFGQSAG 221

  Fly   208 GSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQ-NEAPAK-TRRLAELLGGGDFGGDSKALLTF 270
            |:||.|...:.|::.||::||..:|....::..: :|..|: :|..|..||......||:.||.|
 Worm   222 GASVDLLCLSPHSRGLFNRAIPMAGNGECDFAMRTSEQQAQLSREFARYLGWEGDDNDSEDLLQF 286

  Fly   271 LQSEKATPTAILANTLKVLSPDERRRHL---PFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLGS 332
            :..:.      |......::|....:|.   ...|.|..:..     |..:.:.:|  :|:. ..
 Worm   287 IDQQP------LYKIEMGINPKRGFKHSQAGSLYFVPNFDGD-----FFPKPLNQL--RKEA-PK 337

  Fly   333 MPVIMGYNSAEGLAIVVKAKQKLEAYEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFNG--QA 395
            |.::.|....|||..:  |...|....:.:.:.:.|..........|.:....:..|:|.|  ..
 Worm   338 MQIMTGTTKYEGLFFI--ALGALSKNPEGIKKFMGRIFKECDYGERADDVLQMVYDFYFKGVHPK 400

  Fly   396 LSKENMDNLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDY--VGGRNLYKKIFQNEDLRG 458
            ..::||..:|....||..:....|...|  ....|..:|||:.||  ..|..:::.:.   ...|
 Worm   401 DHEKNMHQIVKFIGDYSINYGTYRLANI--MTDLQHDVYFYQFDYHNSAGFGVFRWLL---PFLG 460

  Fly   459 VAHADDICYLFQMAG----DETEMNRDDLMVTERLCEMWANFARDGKP------SPIWKPVKKPH 513
            ..|..::.|:.   |    .:...|.:|..:...:...:.|||:.|.|      :..|:.....|
 Worm   461 STHCTEMRYVL---GKGIISKFRPNDNDKKMLHVMTTYFTNFAKYGNPNGENQETGEWQKHDSAH 522

  Fly   514 NGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRRYRSENFEAVRA 560
            .....::|   :|         |.|.::    .|:..|:|.::.:||
 Worm   523 PFRHFKID---LD---------DSEMVE----DYQERRAELWDKLRA 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	165/548 (30%)
cest-27	NP_871861.2	COesterase	29..548	CDD:395084	168/560 (30%)