Protein Alignment clt and AADACL3

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001096640.2
• Gene: AADACL3 / 126767
• HGNCID: 32037
• Length: 407
• Species: Homo sapiens
• Alignment Length: 108
• Identity: 29/108 - (26%)
• Similarity: 54/108 - (50%)
• Gaps: 9/108 - (8%)

  Fly   102 LNVYAPKVKSTRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLMEQEVIVVTLNYRLGALGFLSLPE 166
            :.:|.||. ||.|..|.:|:.||||...|:..:.....::|.::...||.      |:|:..||:
Human    99 VKLYQPKA-STCTLKPGIVYYHGGGGVMGSLKTHHGICSRLCKESDSVVL------AVGYRKLPK 156

  Fly   167 EGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAGGS 209
            ...  .:.::|..:|.....:::.::..||..|.:.|:|.||:
Human   157 HKF--PVPVRDCLVATIHFLKSLDAYGVDPARVVVCGDSFGGA 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	29/108 (27%)
AADACL3	NP_001096640.2	Abhydrolase_3	115..378	CDD:400284	22/91 (24%)
		Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole. /evidence=ECO:0000250|UniProtKB:Q5NUF3	119..121		1/1 (100%)