Protein Alignment clt and Cel

DIOPT Version :9

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_034015.1
• Gene: Cel / 12613
• MGIID: 88374
• Length: 599
• Species: Mus musculus
• Alignment Length: 583
• Identity: 173/583 - (29%)
• Similarity: 260/583 - (44%)
• Gaps: 91/583 - (15%)

  Fly    15 CSSMKVKVPVKQGVLVGRQKK--LVNGLEYNSFLGVPYA-----EPPVGELRFRSPRPLERFQKQ 72
            |::....|..:.|.:.|..||  |:.|...:.|.|:|:|     |.|.....::.......|:|:
Mouse    19 CAAKLGAVYTEGGFVEGVNKKLSLLGGDSVDIFKGIPFATAKTLENPQRHPGWQGTLKATNFKKR 83

  Fly    73 ELDCSKEGNVSYQRDPFTLEVAGSEDCLFLNVYAPK-VKSTRTPLPVMVWIHGGGFFFGNGNSDF 136
            .|..:...:.:|          |.||||:||::.|: .|.....|||||||:||.|..|:|....
Mouse    84 CLQATITQDNTY----------GQEDCLYLNIWVPQGRKQVSHNLPVMVWIYGGAFLMGSGQGAN 138

  Fly   137 HFPAKLMEQE-------VIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNG 194
            .....|.:.|       |||||.|||:|.|||||..:..:.||.||:||.:|:.||:.|||:|.|
Mouse   139 FLKNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNFGLRDQHMAIAWVKRNIAAFGG 203

  Fly   195 DPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLG--G 257
            ||:|:|:||||||.:||.|.|.:.:.|.|..:||.|||.|...|..|.......:.:|:.:|  .
Mouse   204 DPDNITIFGESAGAASVSLQTLSPYNKGLIRRAISQSGMALSPWAIQKNPLFWAKTIAKKVGCPT 268

  Fly   258 GDFGGDSKALLTFLQSEKAT-PTAI-LANTLKVLSPDERRRHLP----FAFKPVVEDSSSPDRFL 316
            .|.|..:..|       |.| |.|: ||..|.|     :::..|    .||.||::....||
Mouse   269 EDTGKMAACL-------KITDPRALTLAYKLPV-----KKQEYPVVHYLAFIPVIDGDFIPD--- 318

  Fly   317 EQDIMELMHKKDCLGSMPVIMGYNSAEG-------LAIVVKAKQKLEAYEDDLARLVPRNLVLDP 374
              |.:.|.:.   ...:..|.|.|:.:|       :..|.|.||.:.  |:|..|||..:.|  .
Mouse   319 --DPINLYNN---TADIDYIAGINNMDGHLFATIDVPAVDKTKQTVT--EEDFYRLVSGHTV--A 374

  Fly   375 QAPEAQEAASDIRAFFFNGQALSKENMDNLVDLF-SDYHFSMDLQRAVEIHASCQTQSPLYFYRL 438
            :..:..:|..||....: .|..|:|||...|..| :|..|.:..:.|:..|.:....:..|.|..
Mouse   375 KGLKGAQATFDIYTESW-AQDPSQENMKKTVVAFETDVLFLIPTEIALAQHKAHAKSAKTYSYLF 438

  Fly   439 DYVGGRNLYKKIFQNEDLRGVAHADDICYLF-QMAGDETEMNRDDLMVTERLCEMWANFARDGKP 502
            .:.....:|.|      ..|..||||:.|:| :...........|..|::.:...|.||||.|.|
Mouse   439 SHPSRMPIYPK------WMGADHADDLQYVFGKPFATPLGYRPQDRAVSKAMIAYWTNFARSGDP 497

  Fly   503 ----SPI---WKPVKKPHNGEPIQLDCLLIDRELKMCSNPDGERMDFWRSMYRRYRSENFEAV 558
                ||:   |.|... .||..:.:...:....:|          :..|..:.::.:..||.:
Mouse   498 NMGNSPVPTHWYPYTL-ENGNYLDITKTITSASMK----------EHLREKFLKFWAVTFEVL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	COesterase	22..543	CDD:278561	169/559 (30%)
Cel	NP_034015.1	COesterase	26..542	CDD:278561	170/567 (30%)
		Aes	<117..>247	CDD:223730	64/129 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	553..599
		4 X 11 AA tandem repeats, O-glycosylated region	559..588

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810