Protein Alignment clt and nlgn4x

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 628
• Identity: 189/628 - (30%)
• Similarity: 268/628 - (42%)
• Gaps: 166/628 - (26%)

  Fly     4 RPCG----RLIFT-------------------RF----CSSMKVKVPVKQGVLVGRQKKL---VN 38
            ||.|    .||||                   ||    |.:....||...|.:.|.:..|   :.
 Frog     3 RPNGLLWLPLIFTPVCVLVNSNLLLWIAALAVRFTIVDCQAQHPIVPTNYGKIRGTRTPLPIEIL 67

  Fly    39 GLEYNSFLGVPYAEPPVGELRFRSPRPLERFQ------------KQELD--------------CS 77
            | ....:||||||.||.||.||:.|.|...:.            .|.||              .:
 Frog    68 G-PVEQYLGVPYASPPTGERRFQPPEPPSSWTGIKNATQFAPVCPQFLDERSLLNDMLPIWFTAN 131

  Fly    78 KEGNVSYQRDPFTLEVAGSEDCLFLNVYAP-----------------------KVKSTRTPLPVM 119
            .:..|||.:|.       :||||:||:|.|                       .:.......|||
 Frog   132 LDTVVSYVQDQ-------NEDCLYLNIYVPTEDGATTKKQADDIANNDRGEDEDIHDPNNKKPVM 189

  Fly   120 VWIHGGGFFFGNGNS-DFHFPAKLMEQEVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALE 183
            |:||||.:..|.||. |....|.  ...|||:|:|||||.|||||..::...||.||.||..||.
 Frog   190 VYIHGGSYMEGTGNMIDGSILAS--HGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALR 252

  Fly   184 WVQENIASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAK- 247
            |::|||.:|.|||..||:||..||.|.|.|.|.:.:::.||.|||:|||||...|.. |..|||
 Frog   253 WIEENIGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAV-NYQPAKY 316

  Fly   248 TRRLAELLGGGDFGGDSKALLTFLQ--------SEKATPTAILANTLKVLSPDERRRHLPFAFKP 304
            ||.||:.:|....  |:..|:..|:        .:..||...               |:  ||.|
 Frog   317 TRILADKVGCDML--DTIDLVECLRDKNYKELIQQSITPATY---------------HI--AFGP 362

  Fly   305 VVEDSSSPDRFLEQDIMELMHKKDCLGSMPVIMGYNSAEGLAIV---VKAKQ--KLEAYEDDLAR 364
            |::....||     |...||.:.:.| :..:::|.|..|||..|   |..:.  .|..::..::.
 Frog   363 VIDGDVIPD-----DPQILMEQGEFL-NYDIMLGVNQGEGLKFVDGMVDNEDGVSLSDFDFSVSN 421

  Fly   365 LVPRNLVLDPQAPEAQEAASDIRAFFFNGQALSKENMD----NLVDLFSDYHFSMDLQRAVEIHA 425
            .|. ||.   ..||.::...:...|.:...| .|||.:    .||.||:|:.:........::||
 Frog   422 FVD-NLY---GYPEGKDTLRETIKFMYTDWA-DKENPETRRKTLVALFTDHQWVAPAVATADLHA 481

  Fly   426 SCQTQSPLYFYRLDYVGGRNLYKKIFQNEDLRGVAHADDICYLF--QMAGDETEM-----NRDDL 483
              :..||.|||.. |...::..|..:.:.     ||.|::.|:|  .|.| .||:     :::|:
 Frog   482 --RYGSPTYFYAF-YHHCQSEMKPTWADS-----AHGDEVPYVFGIPMIG-PTELFNCNFSKNDV 537

  Fly   484 MVTERLCEMWANFARDGKPSPIWKPV--------KKPHNGEPI 518
            |::..:...|.|||:.|.|:   |||        .||:..|.:
 Frog   538 MLSAVVMTYWTNFAKTGDPN---KPVPQDTKFIHTKPNRFEEV 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	179/583 (31%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:395084	179/585 (31%)