Protein Alignment clt and nlgn4xb

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001159809.1
• Gene: nlgn4xb / 100147967
• ZFINID: ZDB-GENE-100309-1
• Length: 795
• Species: Danio rerio
• Alignment Length: 545
• Identity: 169/545 - (31%)
• Similarity: 258/545 - (47%)
• Gaps: 95/545 - (17%)

  Fly    26 QGVLVGRQKKLVNGLEYNSFLGVPYAEPPVGELRFRSPRP----------------LERFQKQEL 74
            :|:.|....:::..:|  .|||||||..|.||.||::|.|                ..:|.:..|
Zfish    33 RGLRVALPSEILGPVE--QFLGVPYAMAPTGERRFQAPEPPLSWPGIRNATQFAPVCPQFLEDRL 95

  Fly    75 ----------DCSKEGNVSYQRDPFTLEVAGSEDCLFLNVYAPKVKSTRTPL---PVMVWIHGGG 126
                      ..:.:...:|..|.       |||||:||:|.|..:.|:...   ||||:||||.
Zfish    96 LLTDMLPVWFTANLDTVATYVHDQ-------SEDCLYLNIYVPTEEETQDDAGLKPVMVYIHGGS 153

  Fly   127 FFFGNGNSDFHFPAKLMEQ--EVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENI 189
            :..|.||.   ....::..  .|||||:|||||.|||||..::...||.||.||..||.||:|||
Zfish   154 YVEGTGNM---IDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKENI 215

  Fly   190 ASFNGDPNNVTLFGESAGGSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAK-TRRLAE 253
            .||:|||..||:||..||.|.|.|.|.:.:::.||.|||:.||||...|.. |..||| ||.|||
Zfish   216 QSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIHSGTALSSWAV-NYQPAKYTRLLAE 279

  Fly   254 LLGGGDFGGDSKALLTFLQSEKATPTAILANTLKVLSPDERRRHLPFAFKPVVEDSSSPDRFLEQ 318
            .:|..:  .|:..|:..|||:         |..:::..:........||.||::....||
Zfish   280 KVGCNE--DDTLELIECLQSK---------NYKELIEQNITPAKYHIAFGPVIDGDVIPD----- 328

  Fly   319 DIMELMHKKDCLGSMPVIMGYNSAEGLAIV---VKAKQKLEA--YEDDLARLVPRNLVLDPQAPE 378
            |...||.:.:.| :..:::|.|..||...|   :.::.::.:  :|..::..|....    ..||
Zfish   329 DPQILMEQGEFL-NYDIMLGVNQGEGYKFVDGILDSEDRVTSNDFEFAISEFVDHLY----GYPE 388

  Fly   379 AQEAASDIRAFFFNGQALSKENMD----NLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLD 439
            .::...:...|.:...| .:||.:    .||.||:|:.:........::||  |..||.|||..
Zfish   389 GKDTLRETIKFMYTDWA-DRENPEMRRKTLVALFTDHQWVAPAVATADLHA--QYGSPTYFYAF- 449

  Fly   440 YVGGRNLYKKIFQNEDLRGVAHADDICYLF--QMAGDETEMN----RDDLMVTERLCEMWANFAR 498
            |...::..|..:.:.     :|.|::.|:|  .|.|.....|    ::|:|::..:...|.|||:
Zfish   450 YHHCQSDMKPAWADS-----SHGDELPYVFGIPMIGPTDLFNCNFSKNDIMLSAVVMTYWTNFAK 509

  Fly   499 DGKPS-PIWKPVK----KPHNGEPI 518
            .|.|: |:.:..|    ||:..|.:
Zfish   510 TGDPNQPVPQDTKFIHTKPNRFEEV 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	169/545 (31%)
nlgn4xb	NP_001159809.1	COesterase	24..567	CDD:395084	169/545 (31%)