Protein Alignment clt and nlgn2b

DIOPT Version :10

• Sequence 1: NP_536784.1
• Gene: clt / 117300
• FlyBaseID: FBgn0000326
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 630
• Identity: 178/630 - (28%)
• Similarity: 272/630 - (43%)
• Gaps: 141/630 - (22%)

  Fly     1 MLLRPCGRLIFTRFCSSMKVKVPVKQGVLVGRQKKLVNGL--EYNSFLGVPYAEPPVGELRFRSP 63
            :.|..|.|...|   ::....|....|.|.|.:|:|.|.:  ....:||||||.|||||.||:.|
Zfish    36 LALSSCQRADLT---TAKHPMVTTGYGKLRGVRKELNNEILGPVEQYLGVPYATPPVGERRFQPP 97

  Fly    64 RPLERFQK-----------------------------QELDCSKEGNVSYQRDPFTLEVAGSEDC 99
            .....:|:                             ..||.:    .:|.::.       ||||
Zfish    98 EAPGSWQEIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAA----AAYVQNQ-------SEDC 151

  Fly   100 LFLNVYAPKVKS--------------------TRTPLPVMVWIHGGGFFFGNGNSDFHFPAKLME 144
            |:||||.|....                    .|...|||::||||.|..|.||.   |.|.::.
Zfish   152 LYLNVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSFMEGTGNM---FDASVLA 213

  Fly   145 Q--EVIVVTLNYRLGALGFLSLPEEGIHGNMGLKDQRLALEWVQENIASFNGDPNNVTLFGESAG 207
            .  .|||||:|||||.|||||..::...||.||.||..||.|:.|||..|.|||..:|:||..||
Zfish   214 AYGNVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAG 278

  Fly   208 GSSVHLHTFARHAKRLFHKAIMQSGTANMEWVFQNEAPAKTRRLAELLGGGDFGGDSKALLTFLQ 272
            .|.|:|...:.|::.||.:||.|||:|...|.........|:.||:.:|.
Zfish   279 ASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTKILAKKVGC--------------- 328

  Fly   273 SEKATPTAILANTLK------VLSPDERRRHLPFAFKPVVEDSSSPDRFLEQDIMELMHKKDCLG 331
              ..:.||.|.:.|:      ::..|.:......||.|||:....||     |...||.:.:.|
Zfish   329 --SYSDTADLVDCLRRKSYRELVDQDVQPARYHIAFGPVVDGDVVPD-----DPEILMQQGEFL- 385

  Fly   332 SMPVIMGYNSAEGLAIV--VKAKQKLEA--YEDDLARLVPRNLVLDPQAPEAQEAASDIRAFFFN 392
            :..:::|.|..|||..|  .:.::.:.|  ::..::..|. ||.   ..||.::...:...|.:.
Zfish   386 NYDILLGVNQGEGLKFVDDNEGEEGISAASFDYTISNFVD-NLY---GYPEGKDILRETIKFMYT 446

  Fly   393 GQALSKENMD----NLVDLFSDYHFSMDLQRAVEIHASCQTQSPLYFYRLDYVGGRNLYKKIFQN 453
            ..| .::|.|    .|:.||:|:.:........::||  :.|||:|||...:      :.:....
Zfish   447 DWA-DRDNGDMRRKTLLALFTDHQWVAPAVATAKLHA--EFQSPVYFYTFHH------HCQTEAR 502

  Fly   454 EDLRGVAHADDICYLF--QMAGDETEM-----NRDDLMVTERLCEMWANFARDGKPS-PIWKPVK 510
            .:....||.|:|.|:|  .|.| .||:     :::|:|::..:...|.|||:.|.|: |:.:..|
Zfish   503 PEWADAAHGDEIPYVFGVPMVG-ATELFPCNFSKNDIMLSAVVMTYWTNFAKTGDPNIPVPQDTK 566

  Fly   511 ----KPHNGEPI--------QLDCLLIDRELKMCSNPDGERMDFW 543
                ||:..|.:        ....|.|..:.::..|....::.||
Zfish   567 FIHTKPNRFEEVIWTKFSSKDKQYLHIGLKPRIRDNYRANKVAFW 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
clt	NP_536784.1	alpha/beta hydrolases	22..543	CDD:473884	172/607 (28%)
nlgn2b	NP_001159808.1	COesterase	52..611	CDD:395084	172/609 (28%)