Protein Alignment AP2M1 and ap2m1

DIOPT Version :10

• Sequence 1: NP_001298127.1
• Gene: AP2M1 / 1173
• HGNCID: 564
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_988975.1
• Gene: ap2m1 / 394572
• XenbaseID: XB-GENE-6258427
• Length: 435
• Species: Xenopus tropicalis
• Alignment Length: 460
• Identity: 432/460 - (93%)
• Similarity: 433/460 - (94%)
• Gaps: 25/460 - (5%)

Human     1 MIGGLFIYNHKGEVLISRVYRDDIGSRQAADSAVFSSSGPFPGEWLEANRRNAVDAFRVNVIHAR 65
            |||||||||||||||||||||||||                         |||||||||||||||
 Frog     1 MIGGLFIYNHKGEVLISRVYRDDIG-------------------------RNAVDAFRVNVIHAR 40

Human    66 QQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNF 130
            |||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||
 Frog    41 QQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNF 105

Human   131 VLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRR 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   106 VLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRR 170

Human   196 NELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETSK 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|
 Frog   171 NELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGKGTADETGK 235

Human   261 SGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK 325
            :||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   236 TGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVREVGRTK 300

Human   326 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQ 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   301 LEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQ 365

Human   391 ISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGI 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   366 ISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGI 430

Human   456 YETRC 460
            |||||
 Frog   431 YETRC 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP2M1	NP_001298127.1	AP2_Mu_N	1..165	CDD:341440	137/163 (84%)
		AP-2_Mu2_Cterm	193..459	CDD:271159	263/265 (99%)
ap2m1	NP_988975.1	AP2_Mu_N	1..140	CDD:341440	137/163 (84%)
		AP-2_Mu2_Cterm	168..434	CDD:271159	263/265 (99%)