Protein Alignment AP2M1 and ap2m1a

DIOPT Version :10

• Sequence 1: NP_001298127.1
• Gene: AP2M1 / 1173
• HGNCID: 564
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_001278284.1
• Gene: ap2m1a / 321051
• ZFINID: ZDB-GENE-030131-9784
• Length: 441
• Species: Danio rerio
• Alignment Length: 466
• Identity: 426/466 - (91%)
• Similarity: 429/466 - (92%)
• Gaps: 31/466 - (6%)

Human     1 MIGGLFIYNHKGEVLISRVYRDDIGSRQAADSAVFSSSGPFPGEWLEANRRNAVDAFRVNVIHAR 65
            |||||||||||||||||||||||||                         |||||||||||||||
Zfish     1 MIGGLFIYNHKGEVLISRVYRDDIG-------------------------RNAVDAFRVNVIHAR 40

Human    66 QQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMAAYFGKISEENIKNNF 130
            |||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||
Zfish    41 QQVRSPVTNIARTSFFHVKRSNIWLAAVTKQNVNAAMVFEFLYKMCDVMTAYFGKISEENIKNNF 105

Human   131 VLIYELLDEILDFGYPQNSETGALKTFITQQGIKSQHQTKEEQSQITSQVTGQIGWRREGIKYRR 195
            ||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||
Zfish   106 VLIYELLDEILDFGYPQNSETGALKTFITQQGIKGQHQTKEEQSQITSQVTGQIGWRREGIKYRR 170

Human   196 NELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIEKQGK-GTADETS 259
            ||||||||||||||||||||||||||||||||||||||||||||||||||||:|||| ||.|:..
Zfish   171 NELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGMPECKFGMNDKIVIDKQGKGGTTDDAG 235

Human   260 K-----SGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYRTTKDIILPFRVIPLVR 319
            |     ||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
Zfish   236 KSELGGSGKQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEYELMRYRTTKDIILPFRVIPLVR 300

Human   320 EVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMA 384
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   301 EVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMA 365

Human   385 GMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRY 449
            |||||||||||||||||||||||||||||||||||||||||||||||||.|||||||||||||||
Zfish   366 GMKESQISAEIELLPTNDKKKWARPPISMNFEVPFAPSGLKVRYLKVFESKLNYSDHDVIKWVRY 430

Human   450 IGRSGIYETRC 460
            |||||||||||
Zfish   431 IGRSGIYETRC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP2M1	NP_001298127.1	AP2_Mu_N	1..165	CDD:341440	137/163 (84%)
		AP-2_Mu2_Cterm	193..459	CDD:271159	258/271 (95%)
ap2m1a	NP_001278284.1	AP2_Mu_N	1..139	CDD:341440	136/162 (84%)
		AP-2_Mu2_Cterm	168..440	CDD:271159	258/271 (95%)