Protein Alignment Dsp1 and TOX

DIOPT Version :9

• Sequence 1: NP_001138203.1
• Gene: Dsp1 / 117294
• FlyBaseID: FBgn0278608
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_055544.1
• Gene: TOX / 9760
• HGNCID: 18988
• Length: 526
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 67/291 - (23%)
• Similarity: 103/291 - (35%)
• Gaps: 85/291 - (29%)

  Fly   113 GSQWWYSAANQGQVDANTAAQLQHQQQQQQQQQQQQQQQHQQQQQMQQQQQQ---------QNV- 167
            |:|  ||:..|       .|.::.:.|....:||.....|.|...:.|.|..         .||
Human   146 GTQ--YSSHPQ-------MAAMRPRGQPADIRQQPGMMPHGQLTTINQSQLSAQLGLNMGGSNVP 201

  Fly   168 INSASPMSRVKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKK 232
            .||.||.....|...|...:                 |.||           .:....:...||:
Human   202 HNSPSPPGSKSATPSPSSSV-----------------HEDE-----------GDDTSKINGGEKR 238

  Fly   233 RFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALN 297
            ...:|.:|.|           .||       ||:|  ||||.|::.:||:..|..|.:..:|..|
Human   239 PASDMGKKPK-----------TPK-------KKKK--KDPNEPQKPVSAYALFFRDTQAAIKGQN 283

  Fly   298 PEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTS----------------- 345
            |....|:::|.:...|..:..|.||.|:...|..|..|.:::..|:.|
Human   284 PNATFGEVSKIVASMWDGLGEEQKQVYKKKTEAAKKEYLKQLAAYRASLVSKSYSEPVDVKTSQP 348

  Fly   346 GKIAMSAPSMQASMQAQAQKAALLAAAAQQQ 376
            .::..|.||:... .:||..|..|::...||
Human   349 PQLINSKPSVFHG-PSQAHSALYLSSHYHQQ 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	9/69 (13%)
		HMGB-UBF_HMG-box	275..339	CDD:238686	18/63 (29%)
TOX	NP_055544.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..178		10/40 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	192..264		26/119 (22%)
		Nuclear localization signal. /evidence=ECO:0000255	237..256		9/38 (24%)
		NHP6B	<257..>360	CDD:227935	26/102 (25%)
		HMG-box	261..>310	CDD:238037	14/48 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810