Protein Alignment Dsp1 and Hmgb2

DIOPT Version :10

• Sequence 1: NP_001138203.1
• Gene: Dsp1 / 117294
• FlyBaseID: FBgn0278608
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_032278.1
• Gene: Hmgb2 / 97165
• MGIID: 96157
• Length: 210
• Species: Mus musculus
• Alignment Length: 216
• Identity: 101/216 - (46%)
• Similarity: 142/216 - (65%)
• Gaps: 16/216 - (7%)

  Fly   182 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 246
            ||||:|::||:|||||||||||||||.:|.|||||:||:||||||..|||.:|.::|:.||.||:
Mouse     8 KPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72

  Fly   247 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGR 311
            .||:|||||||.  .:|||    ||||||||..||||.||::.|.|:|..:|...:||.||:||.
Mouse    73 REMKNYVPPKGD--KKGKK----KDPNAPKRPPSAFFLFCSENRPKIKIEHPGLSIGDTAKKLGE 131

  Fly   312 KWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGK--IAMSAPSMQASMQAQAQKAALLAAAAQ 374
            .||:...:.||.||..|.:.|.:||:::..|:..||  .....|......:.:.:        .:
Mouse   132 MWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNE--------PE 188

  Fly   375 QQHQQLEEQHDDDDGDGDDDE 395
            .:.::.||:.::||.:.::||
Mouse   189 DEEEEEEEEEEEDDEEEEEDE 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box_HMGB_rpt1	182..250	CDD:438794	46/67 (69%)
		HMG-box_NHP6-like	262..342	CDD:438792	37/79 (47%)
Hmgb2	NP_032278.1	HMG-box_HMGB_rpt1	8..76	CDD:438794	46/67 (69%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	71..102		22/36 (61%)
		HMG-box_HMGB_rpt2	93..163	CDD:438795	31/69 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..210		10/56 (18%)
		Required for chemotactic activity. /evidence=ECO:0000250|UniProtKB:P26583	165..180		3/14 (21%)