DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dsp1 and Tfam

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_112616.2	Gene:	Tfam / 83474	RGDID:	620682	Length:	244	Species:	Rattus norvegicus

Alignment Length:	176	Identity:	48/176 - (27%)
Similarity:	81/176 - (46%)	Gaps:	21/176 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 PRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEA 247
            |:..|::|..|......:.|.||||..|  :|..||.|..|:.:.:.|||.:....:.:.:.|:.
  Rat    49 PKKPMSSYLRFSTEQLPKFKAKHPDAKV--SELIRKIAAMWRELPEAEKKVYEADFKAEWKVYKE 111

  Fly   248 EMQNY---VPP-------KGAVVGRGKKRKQIKDP-----NAPKRSLSAFFWFCNDERNKVKALN 297
            .:..|   :.|       |.|...|.||:.|||..     ..|||..||:..:.::...:.|
  Rat   112 AVSKYKEQLTPSQLMGLEKEARQKRLKKKAQIKRRELILLGKPKRPRSAYNIYVSESFQEAK--- 173

  Fly   298 PEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYK 343
            .|...|.: |.:.:.|.::..:.||.|..:|:.|:.||:.||..::
  Rat   174 DESAQGKL-KLVNQAWKNLSHDEKQAYIQLAKDDRIRYDNEMKSWE 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	19/68 (28%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	17/63 (27%)
Tfam	NP_112616.2	NHP6B	<46..215	CDD:227935	47/171 (27%)
		HMG_box	49..116	CDD:395407	19/68 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	221..244
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48112
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910