DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and Hmg20a

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_080088.1	Gene:	Hmg20a / 66867	MGIID:	1914117	Length:	346	Species:	Mus musculus

Alignment Length:	146	Identity:	50/146 - (34%)
Similarity:	78/146 - (53%)	Gaps:	10/146 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   239 EKDKQRYEAEMQNYVPPKGAVVGRGKKRKQ-IKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGV 302
            |.::||.|.|.::    |.....:|:|||: ::|.||||..|:.:..|.|:.|.:::|..||...
Mouse    69 EGNEQRPEDEQRS----KRGGWSKGRKRKKPLRDSNAPKSPLTGYVRFMNERREQLRAKRPEVPF 129

  Fly   303 GDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEY-KTSGKIAMSAPSMQASMQAQAQKA 366
            .:|.:.||.:||.:.||.||:|...|:|||.||.:|:.:| ||......|    :.:...|..|:
Mouse   130 PEITRMLGNEWSKLPPEEKQRYLDEADRDKERYMKELEQYQKTEAYKVFS----RKTQDRQKGKS 190

  Fly   367 ALLAAAAQQQHQQLEE 382
            ....||.|..|...:|
Mouse   191 HRQDAARQATHDHEKE 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	5/12 (42%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	25/63 (40%)
Hmg20a	NP_080088.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..112		16/46 (35%)
		DUF5401	<76..312	CDD:375164	47/139 (34%)
		HMGB-UBF_HMG-box	102..167	CDD:238686	26/64 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..210		8/33 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3288
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840