DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and RGD1559962

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_008756867.1	Gene:	RGD1559962 / 498988	RGDID:	1559962	Length:	209	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	101/216 - (46%)
Similarity:	141/216 - (65%)	Gaps:	17/216 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 246
            ||||:|::||:||||||||||.||||.:|.|||||:||:||||||..|||.:|.::|:.||.||:
  Rat     8 KPRGKMSSYAFFVQTCREEHKNKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72

  Fly   247 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGR 311
            .||:|||||||.  .:|||    ||||||||..||||.||::.|.|:|:.:|...:||.||:||.
  Rat    73 REMKNYVPPKGD--KKGKK----KDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGE 131

  Fly   312 KWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGK--IAMSAPSMQASMQAQAQKAALLAAAAQ 374
            .||:...:.||.||..|.:.|..||:::..|:..||  :....|......:.:.:         .
  Rat   132 MWSEQSAKDKQPYEQKAAKLKEEYEKDIAAYRAKGKSEVGKKGPGRPTGSKKKNE---------P 187

  Fly   375 QQHQQLEEQHDDDDGDGDDDE 395
            :..::.||:.|:|:.:.|:||
  Rat   188 EDEEEEEEEDDEDEEEEDEDE 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	46/69 (67%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	29/63 (46%)
RGD1559962	XP_008756867.1	HMG-box	7..78	CDD:294061	46/69 (67%)
RGD1559962	XP_008756867.1	HMG_box	95..162	CDD:278906	29/66 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5799
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3551
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000133
OrthoInspector	1	1.000	-	-		otm45117
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48112
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X111
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.960