DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and RGD1561694

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_038948739.1	Gene:	RGD1561694 / 498388	RGDID:	1561694	Length:	209	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	100/218 - (45%)
Similarity:	143/218 - (65%)	Gaps:	21/218 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 246
            ||||:|:.||:|||||||||||||||.:|.|||||:||:||||||..|||.:|.::|:.||.||:
  Rat     8 KPRGKMSLYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDLAKSDKARYD 72

  Fly   247 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGR 311
            .||:|||||||     .||.|: ||||||||..||||.||::.|.|:|:.:|...:||.||:||.
  Rat    73 REMKNYVPPKG-----NKKGKK-KDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLGE 131

  Fly   312 KWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGK--IAMSAPSMQASMQAQAQKAALLAAAAQ 374
            .||:...:.||.||..|.:.|.:||:::..|:..||  :....|...             ..:.:
  Rat   132 MWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEVGKKGPGRP-------------TGSKK 183

  Fly   375 QQHQQLEEQHDDDDGDGDDDENQ 397
            :...:.||:.:::||:.:::|::
  Rat   184 KNEPEDEEEEEEEDGEDEEEEDE 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	47/69 (68%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	29/63 (46%)
RGD1561694	XP_038948739.1	HMG_box_2	6..78	CDD:401091	47/69 (68%)
RGD1561694	XP_038948739.1	HMG_box	95..162	CDD:395407	29/66 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5799
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3551
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000133
OrthoInspector	1	1.000	-	-		otm45117
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48112
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X111
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.060