DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and ssrp1a

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_997967.2	Gene:	ssrp1a / 386844	ZFINID:	ZDB-GENE-031118-9	Length:	705	Species:	Danio rerio

Alignment Length:	450	Identity:	86/450 - (19%)
Similarity:	164/450 - (36%)	Gaps:	100/450 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLMNIHQPTIDQQTIQHYQQQLAAQQQQQVQQ------QQLQQHQVVVQQNQQQAHQNSSNTTAG 59
            :.:|:.:..::::    |:.:|:......:.:      :.|...::.|..| .|.|..|...|..
Zfish   286 LALNMSEDEVEKR----YEGKLSKNMSGPLYEIVSRVMKALVNRKITVPGN-FQGHSGSQCITCA 345

  Fly    60 VGTQQLFTYKMASSF-----PNPATTMAQVVATSNAAGTT---GYDYRLNMAQAAAAAAVPGSQW 116
            ........|.:...|     |.......::...:.|.|||   .:|:.:...|        .:|:
Zfish   346 YKASSGLLYPLERGFIYVHKPPVHLRFEEISCVNFARGTTTTRSFDFEIETKQ--------NNQF 402

  Fly   117 WYSAANQGQ----VDANTAAQL-------QHQQQQQQQQQQQQQQQHQQQQQMQQQQQQQNVINS 170
            .:|...:.:    .|...|.:|       :...:..:......:.||.
Zfish   403 TFSNIEREEYGKLFDFVNAKKLTIKNRGFKEGMKGAEDYSDSDEDQHD----------------- 450

  Fly   171 ASPMSRVKADAKPRGRMTAYAYFVQTCREE-----HKKKHPDETVIFAEFSRKCAERW---KTMV 227
             :.:.|:|.:.|              .|||     ..:...||:....|......|.:   .::.
Zfish   451 -AYLERMKEEGK--------------IREEGDGSDDSEGDSDESFNPGEEDDDVPEEYDSNASVS 500

  Fly   228 DKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNK 292
            |.|........|..|::.|.:.:..|..|..  .:.:|.|::||..||||.:||:..:.|..|.:
Zfish   501 DSEGDDGDSEDEGKKKKVEKKPKKVVKEKKE--RKPRKEKKVKDAAAPKRPMSAYMLWLNGNRER 563

  Fly   293 VKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAP---- 353
            :|:.||...:.:|:|:.|..|..:..:.|::::..||..|.:||:.|.|||.||..|.:|.
Zfish   564 IKSENPGISITEISKKAGEMWKQLGKDKKEEWDKKAEEAKRQYEKAMKEYKESGGGAAAATKEKK 628

  Fly   354 ----SMQASMQAQAQKAALLAAA----AQQQHQQLEEQHDDDDGD--------GDDDENQ 397
                .::|..::..:|.......    ..::....||...:.|.|        .||||.:
Zfish   629 KKGGKVEAKKKSGGEKEKKKEGGNDSFKSKEFISSEESSSESDHDRGSKRKASDDDDEEE 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	13/77 (17%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	20/63 (32%)
ssrp1a	NP_997967.2	POB3	21..512	CDD:227494	38/270 (14%)
		SSrecog	75..285	CDD:281523
		PH2_SSRP1-like	333..428	CDD:270051	18/102 (18%)
		HMG_box	546..613	CDD:278906	21/66 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910