DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and hmg20a

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001082803.1	Gene:	hmg20a / 326908	ZFINID:	ZDB-GENE-030131-5107	Length:	291	Species:	Danio rerio

Alignment Length:	130	Identity:	37/130 - (28%)
Similarity:	70/130 - (53%)	Gaps:	4/130 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 PKGAVVGRGKKRKQ-IKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDP 318
            |:.:...:|::||: :||.||||..|:.:..|.|:.|.:::|..|:....:|.:.||.:||.:..
Zfish    24 PRRSSWTKGRRRKKPLKDSNAPKAPLTGYVRFMNERREQLRAERPDVPFPEITRMLGNEWSKLPA 88

  Fly   319 EVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQHQQLEEQ 383
            :.||:|...|::||.||.||:.:|:.:......:..:|...:.:..:.   .|..|...:.|.|:
Zfish    89 DEKQRYLDEADKDKERYMRELEQYQKTEAYKHFSRKVQEKQKGKRHRG---DAGRQAPGESLHEK 150

Fly 384 383
Zfish 151 150

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	22/63 (35%)
hmg20a	NP_001082803.1	HMGB-UBF_HMG-box	45..110	CDD:238686	23/64 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3288
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840