Protein Alignment Dsp1 and HMGB3

DIOPT Version :9

• Sequence 1: NP_001138203.1
• Gene: Dsp1 / 117294
• FlyBaseID: FBgn0278608
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_001288160.1
• Gene: HMGB3 / 3149
• HGNCID: 5004
• Length: 220
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 96/214 - (44%)
• Similarity: 140/214 - (65%)
• Gaps: 21/214 - (9%)

  Fly   182 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 246
            ||:|:|:|||:||||||||||||:|:..|.|||||:||:||||||..|||.:|.|||:.||.||:
Human    28 KPKGKMSAYAFFVQTCREEHKKKNPEVPVNFAEFSKKCSERWKTMSGKEKSKFDEMAKADKVRYD 92

  Fly   247 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGR 311
            .||::|.|.||     |||:   ||||||||..|.||.||::.|.|:|:.||...:||:||:||.
Human    93 REMKDYGPAKG-----GKKK---KDPNAPKRPPSGFFLFCSEFRPKIKSTNPGISIGDVAKKLGE 149

  Fly   312 KWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQ 376
            .|::::...||.|.:.|.:.|.:||:::.:||:.||.             ...|.....|..:.:
Human   150 MWNNLNDSEKQPYITKAAKLKEKYEKDVADYKSKGKF-------------DGAKGPAKVARKKVE 201

  Fly   377 HQQLEEQHDDDDGDGDDDE 395
            .:..||:.::::.:.::||
Human   202 EEDEEEEEEEEEEEEEEDE 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	47/69 (68%)
		HMGB-UBF_HMG-box	275..339	CDD:238686	27/63 (43%)
HMGB3	NP_001288160.1	HMG_box_2	33..98	CDD:370242	44/64 (69%)
		HMG_box	113..180	CDD:366139	27/66 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149771
Domainoid	1	1.000	117	1.000	Domainoid score	I5909
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3638
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000133
OrthoInspector	1	1.000	-	-		otm40983
orthoMCL	1	0.900	-	-		OOG6_100324
Panther	1	1.100	-	-	O	PTHR48112
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3288
SonicParanoid	1	1.000	-	-		X111
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.780