DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and Tox4

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_075923.2	Gene:	Tox4 / 268741	MGIID:	1915389	Length:	619	Species:	Mus musculus

Alignment Length:	130	Identity:	36/130 - (27%)
Similarity:	60/130 - (46%)	Gaps:	1/130 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 HEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPE 299
            ||....|.:|.....:..|...|......||||: ||||.|::.:||:..|..|.:..:|..||.
Mouse   184 HEDGVDDFRRQLPAQKTVVVETGKKQKAPKKRKK-KDPNEPQKPVSAYALFFRDTQAAIKGQNPN 247

  Fly   300 FGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQ 364
            ...|:::|.:...|..:..|.||.|:...|..|..|.:.:..||.:.:...:..:::.....|:|
Mouse   248 ATFGEVSKIVASMWDSLGEEQKQVYKRKTEAAKKEYLKALAAYKDNQECQATVETVELDPVPQSQ 312

Fly 365 364
Mouse 313 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	4/16 (25%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	18/63 (29%)
Tox4	NP_075923.2	NHP6B	140..>306	CDD:227935	34/122 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	155..227		15/43 (35%)
		Nuclear localization signal. /evidence=ECO:0000255	213..218		4/5 (80%)
		HMG-box	223..288	CDD:238037	18/64 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..335		2/7 (29%)
		PHA03160	<464..530	CDD:165431
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810