DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and Ubtf

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001349473.1	Gene:	Ubtf / 21429	MGIID:	98512	Length:	764	Species:	Mus musculus

Alignment Length:	327	Identity:	61/327 - (18%)
Similarity:	127/327 - (38%)	Gaps:	70/327 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 GSQWWYSAANQGQVDANTAAQLQHQQQQQQQQQQQQQQQHQQQQ---QMQQQQQQQNVINSASPM 174
            |.||       .|:......:..|:..:|:::.::..:.:.|:.   .:.::...::.:..|...
Mouse   231 GKQW-------SQLSDKKRLKWIHKALEQRKEYEEIMRDYIQKHPELNISEEGITKSTLTKAERQ 288

  Fly   175 SRVKADAKP-RGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMA 238
            .:.|.|.:| :....:|:.:........|.....|.::.      |:::||.:..|||..:|:..
Mouse   289 LKDKFDGRPTKPPPNSYSLYCAELMANMKDVPSTERMVL------CSQQWKLLSQKEKDAYHKKC 347

  Fly   239 EKDKQRYEAEMQNYV-----PPKGAVVGRGK----KRKQIKDP--------------NAPKRSLS 280
            ::.|:.||.|:..::     ..:..|:|..|    .:||...|              ..|||.:|
Mouse   348 DQKKKDYEVELLRFLESLPEEEQQRVLGEEKMLNINKKQTTSPASKKPSQEGGKGGSEKPKRPVS 412

  Fly   281 AFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYERE------- 338
            |.|.|..::|.:::...||....::.:.|.|.|:|:..:.|.||::.....||:.||:
Mouse   413 AMFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGGERED 477

  Fly   339 -----------------------MTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQHQQL 380
                                   :..:|.....|:.|..|..:...:.:|...:..||:.|.:..
Mouse   478 RGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYE 542

  Fly   381 EE 382
            .|
Mouse   543 RE 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	15/70 (21%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	21/93 (23%)
Ubtf	NP_001349473.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		HMG_box	112..179	CDD:395407
		HMGB-UBF_HMG-box	196..261	CDD:238686	6/36 (17%)
		HMGB-UBF_HMG-box	299..358	CDD:238686	13/64 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	370..411		9/40 (23%)
		HMGB-UBF_HMG-box	407..470	CDD:238686	20/62 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	456..487		5/30 (17%)
		HMG_box_5	479..562	CDD:373364	9/66 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	546..576
		HMGB-UBF_HMG-box	569..631	CDD:238686
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810