DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and hmg-3

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_491688.1	Gene:	hmg-3 / 172250	WormBaseID:	WBGene00001973	Length:	689	Species:	Caenorhabditis elegans

Alignment Length:	290	Identity:	77/290 - (26%)
Similarity:	117/290 - (40%)	Gaps:	72/290 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 YSAANQGQVDA-NTAAQLQHQQQQQQQQQQQQQQQHQQQQQMQQQQQQQNVINSASPM------S 175
            |.::::..:|. .:..:.:.::|......:...:.:...:.|::|:..::....:...      |
Worm   440 YGSSDEDDIDPYKSTVKAEGREQDDDSDDESTDEDYDLDKDMKKQKNDKDSSEGSGSEPDDEYDS 504

  Fly   176 RVKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEK 240
            ..:.||...|                 :..|||..|          ..|....||||...|..||
Worm   505 GSEKDASGTG-----------------ESDPDEENI----------EPKKKESKEKKNKREKKEK 542

  Fly   241 DKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAF-FWFCNDERNKVKALNPEFG--V 302
                         |.|...|.:|||   .||||.|||:.:|: .|| |..||.:|    |.|  :
Worm   543 -------------PVKEKAVKKGKK---TKDPNEPKRATTAYIIWF-NANRNSMK----EDGDTL 586

  Fly   303 GDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTS--GKIAMSAPSMQASMQAQAQK 365
            ||:||:.|.||..:..:.|:::...|.:||||||.||.|||.:  |....|.||.:.|......|
Worm   587 GDVAKKAGAKWKSMSADDKKEWNDKAAQDKARYEAEMKEYKKNGGGVEKASGPSTKKSSDQSPGK 651

  Fly   366 AALLAAAAQQQHQQLEEQHDDDDGDGDDDE 395
                        |...::|..|..|.||||
Worm   652 ------------QFKSKEHISDTDDSDDDE 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	13/69 (19%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	27/66 (41%)
hmg-3	NP_491688.1	POB3	20..497	CDD:227494	5/56 (9%)
		SSrecog	75..285	CDD:281523
		PH2_SSRP1-like	332..429	CDD:270051
		HMGB-UBF_HMG-box	561..624	CDD:238686	28/67 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910