DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and Hmg20b

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006513311.1	Gene:	Hmg20b / 15353	MGIID:	1341190	Length:	415	Species:	Mus musculus

Alignment Length:	166	Identity:	46/166 - (27%)
Similarity:	77/166 - (46%)	Gaps:	17/166 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 VDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERN 291
            |.:|:.......||..|..|       |.|.....:|||||:|. ||.||..::.:..|.|:.|.
Mouse    30 VKQERSEGSRAGEKGPQEEE-------PVKKRGWPKGKKRKKIL-PNGPKAPVTGYVRFLNERRE 86

  Fly   292 KVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQ 356
            :::..:|:....:|.|.||.:||.:.|..||:|...||::|.:|.:|:..|:.|....:....:|
Mouse    87 QIRTRHPDLPFPEITKMLGAEWSKLQPAEKQRYLDEAEKEKQQYLKELWAYQQSEAYKVCTEKIQ 151

  Fly   357 AS-MQAQAQKAALLAAAAQQQHQQLEEQHDDDDGDG 391
            .: ::.:...:.|:        ..|...|...|.||
Mouse   152 ENKIKKEDSSSGLM--------NTLLNGHKGVDCDG 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	6/24 (25%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	20/63 (32%)
Hmg20b	XP_006513311.1	HMGB-UBF_HMG-box	70..134	CDD:238686	20/63 (32%)
		OmpH	190..>254	CDD:214922
		FAM222A	<314..>400	CDD:373691
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3288
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930