DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dsp1 and LOC108350839

DIOPT Version :9

Sequence 1:	NP_001138203.1	Gene:	Dsp1 / 117294	FlyBaseID:	FBgn0278608	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_017448593.1	Gene:	LOC108350839 / 108350839	RGDID:	11440908	Length:	214	Species:	Rattus norvegicus

Alignment Length:	216	Identity:	93/216 - (43%)
Similarity:	141/216 - (65%)	Gaps:	19/216 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 KPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYE 246
            ||||:|:::|:|||||||||||||.:.:|.|:|||:||:||||||..|||.:|.:||:.||.|||
  Rat     8 KPRGKMSSHAFFVQTCREEHKKKHLNASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYE 72

  Fly   247 AEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGR 311
            .||:.|:|||      |:.:|:.|||||.||..||||.||::.|.|:|..:|...:||:||:||.
  Rat    73 REMKTYIPPK------GETKKKFKDPNALKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGE 131

  Fly   312 KWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQ 376
            .|::...:.||..|..|.:.|.:||:::..|:..||             ..|.|..::.|...::
  Rat   132 MWTNTAVDDKQPCEKKAAKLKEKYEKDIAAYRAKGK-------------PDAAKKGVVKAEKSKK 183

  Fly   377 HQQLEEQHDDDDGDGDDDENQ 397
            .::.|:..:|:|.:.:::||:
  Rat   184 KKEEEDDEEDEDEEEEEEENE 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dsp1	NP_001138203.1	HMG-box	182..252	CDD:294061	45/69 (65%)
Dsp1	NP_001138203.1	HMGB-UBF_HMG-box	275..339	CDD:238686	26/63 (41%)
LOC108350839	XP_017448593.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I5799
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3551
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000133
OrthoInspector	1	1.000	-	-		otm45117
orthoMCL	1	0.900	-	-		OOG6_100324
Panther	1	1.100	-	-	LDO	PTHR48112
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X111
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.860