Protein Alignment Mat1a and Sam-S

DIOPT Version :9

• Sequence 1: NP_598414.1
• Gene: Mat1a / 11720
• MGIID: 88017
• Length: 396
• Species: Mus musculus
• Sequence 2: NP_524923.1
• Gene: Sam-S / 48552
• FlyBaseID: FBgn0005278
• Length: 408
• Species: Drosophila melanogaster
• Alignment Length: 381
• Identity: 280/381 - (73%)
• Similarity: 342/381 - (89%)
• Gaps: 1/381 - (0%)

Mouse    15 EEGA-FMFTSESVGEGHPDKICDQISDAVLDAHLKQDPNAKVACETVCKTGMVLLCGEITSVAMV 78
            |:|| |:|||||||||||||:|||||||:||||||||||||||||||.||||:||||||||.|:|
  Fly    24 EDGATFLFTSESVGEGHPDKMCDQISDAILDAHLKQDPNAKVACETVAKTGMILLCGEITSKAVV 88

Mouse    79 DYQRVVRDTIKHIGYDDSAKGFDFKTCNVLVALEQQSPDIAQCVHLDRNEEDVGAGDQGLMFGYA 143
            |||:|||:|::|||||||:||||:||.|:|||:|||||:||..||::|.||||||||||:|||||
  Fly    89 DYQKVVRETVQHIGYDDSSKGFDWKTLNLLVAIEQQSPNIANGVHINREEEDVGAGDQGIMFGYA 153

Mouse   144 TDETEECMPLTIVLAHKLNTRIADLRRSGVLPWLRPDSKTQVTVQYMQDNGAVIPVRIHTIVISV 208
            |||||||||||:|||||||.:||:||||.|..|.|||||||||.:|:.:.|:.:|.|:||||:|:
  Fly   154 TDETEECMPLTVVLAHKLNEKIAELRRSDVFWWARPDSKTQVTCEYLFNQGSAVPKRVHTIVVSM 218

Mouse   209 QHNEDITLEAMQEALKEQVIKAVVPAKYLDEDTVYHLQPSGRFVIGGPQGDAGVTGRKIIVDTYG 273
            ||:|.|:||.::..:.|:|:|.|:||||:|.:|:.|:.|.|.||||||.||||:|||||||||||
  Fly   219 QHSEKISLETLRSEVMEKVVKVVIPAKYIDANTIVHINPCGLFVIGGPMGDAGLTGRKIIVDTYG 283

Mouse   274 GWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKAGLCRRVLVQVSYAIGVAEPLSISIFTYGT 338
            ||||||||||||||:||||||||||||||||||||||||:|.|||||||||:||||||::|.|||
  Fly   284 GWGAHGGGAFSGKDFTKVDRSAAYAARWVAKSLVKAGLCKRCLVQVSYAIGLAEPLSITVFDYGT 348

Mouse   339 SNKTERELLEVVNKNFDLRPGVIVRDLDLKKPIYQKTACYGHFGRSEFPWEVPKKL 394
            |:|:::|||:::.:|||||||.||:||:|::||||:|:.||||||:.|.||..|.|
  Fly   349 SHKSQKELLDIIRRNFDLRPGKIVKDLNLRQPIYQRTSTYGHFGRAGFSWEEAKPL 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mat1a	NP_598414.1	PTZ00104	17..394	CDD:240268	278/377 (74%)
		Flexible loop. /evidence=ECO:0000250|UniProtKB:P0A817	114..126		7/11 (64%)
Sam-S	NP_524923.1	PTZ00104	28..408	CDD:240268	277/377 (73%)
		S-AdoMet_synt_N	28..125	CDD:278846	79/96 (82%)
		S-AdoMet_synt_M	140..261	CDD:280867	76/120 (63%)
		S-AdoMet_synt_C	263..399	CDD:280868	106/135 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837260
Domainoid	1	1.000	238	1.000	Domainoid score	I2294
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	604	1.000	Inparanoid score	I930
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61243
OrthoDB	1	1.010	-	-		D357186at33208
OrthoFinder	1	1.000	-	-		FOG0000746
OrthoInspector	1	1.000	-	-		otm43992
orthoMCL	1	0.900	-	-		OOG6_100388
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R708
SonicParanoid	1	1.000	-	-		X478
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	11.840